Research Associate 1 MS
Supports a team of investigators involved in an Aligning Science Across Parkinson’s project through the development and maintenance of genome edited human induced stem cell lines and specialized cell types derived from them. Conducts research requiring specialized techniques including: the generation of genetically modified human cells (iPSCs and cell lines) via CRISPR-mediated genome editing methods, the growth and differentiation of human iPSCs into specialized cell types of the nervous system, the isolation and analysis of RNA and DNA from such cells. Takes responsibility for day-to-day laboratory operations related to these research efforts. Trains incoming laboratory personnel (graduate students and postdocs) in the use of these cells. Maintains an inventory of cell lines and coordinates their sharing between labs.
- Recommends the design and implementation of procedures and protocols under the direction of a higher-level authority.
- Investigates, analyzes, and reaches preliminary scientific conclusions related to research planning
- Ensures data results are compiled, analyzed, and presented properly.
- Analyzes, develops and interprets scientific results. Maintains clear documentation of results. Prepares scientific reports and papers for research proposals and published reports
- Performs independent research and laboratory techniques and participates in experimental research planning.
- Interacts with internal contacts including the PI, research assistants, graduate students, Radiation Safety and Biological Safety officers, and Animal Care personnel to discuss and evaluate research results and to ensure the smooth and safe operation of the laboratory.
- Interacts with external contacts such as researchers at other institutions, staff at biotechnology and reagents companies to consult on research methods and to keep abreast of product information and developments.
- May perform other duties as assigned.
Required Education and Experience
Master’s Degree in a scientific discipline and one year experience or an equivalent combination of education and experience.
Required Skill/Ability 1:
Skilled with methods for the growth, maintenance and genetic modification of mammalian cells.
Required Skill/Ability 2:
Ability to analyze and interpret scientific results and present at regular laboratory meetings.
Required Skill/Ability 3:
Ability to train incoming lab personnel in experimental methods developed in laboratory.
Required Skill/Ability 4:
High degree of reliability and attention to details.
Required Skill/Ability 5:
Excellent organizational, interpersonal and communication skills.
Preferred Education, Experience and Skills:
Experience with the maintenance and differentiation of human induced pluripotent stem cells. Experience with fluorescence activated cell sorting. Experience with isolation and analysis of mRNA, DNA and protein from mammalian cells. Experience with the growth of primary cultures of mammalian neurons.
Weekend Hours Required?
Evening Hours Required?
Background Check Requirements
All candidates for employment will be subject to pre-employment background screening for this position, which may include motor vehicle, DOT certification, drug testing and credit checks based on the position description and job requirements. All offers are contingent upon the successful completion of the background check. Please visit www.yale.edu/hronline/careers/screening/faqs.html for additional information on the background check requirements and process.
The intent of this job description is to provide a representative summary of the essential functions that will be required of the position and should not be construed as a declaration of specific duties and responsibilities of the particular position. Employees will be assigned specific job-related duties through their hiring departments.
Affirmative Action Statement:
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