Screening Specialist B

Location
Pennsylvania, United States
Posted
09 Dec 2020
End of advertisement period
09 Feb 2021
Ref
JR00026648
Contract Type
Permanent
Hours
Full Time

University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Job Description Summary

The primary mission of the High-Throughput Screening Core (HTSC) is to provide the Perelman School of Medicine (PSOM) community with high-throughput screening capabilities to identify genes or organic small molecule modulators of signaling pathways, cellular phenotypes, and protein function in models of human disease. The successful candidate will be a highly motivated individual with a Bachelor’s degree and 2 years of experience or equivalent combinations of education and experience, strong organizational skills, effective communication skills, the ability to problem-solve, work independently, and work in a team environment. They will work under the supervision of the Core Directors to execute experiments that optimize and validate cell and biochemical assays in high-density formats (i.e. 384 well microtiter plates).

Job Description

The candidate will work in the UPenn High-Throughput Screening Core (HTSC) in the Perelman School of Medicine (PSOM).  The primary mission of the core is to provide the PSOM community with high-throughput screening capabilities to identify genes or organic small molecule modulators of signaling pathways, cellular phenotypes, and protein function in models of human disease. The successful candidate will work under the supervision of the Core Directors to execute experiments that optimize and validate cell and biochemical assays in high-density formats (i.e. 384 well microtiter plates).  Specific responsibilities will include moderately complex procedures in mammalian cell biology, and high-throughput genetic/chemical screening.  The candidate will be required to operate and maintain automated laboratory robotic workstations related to high-throughput screening; prepare and manage libraries of siRNA, shRNA, cDNA, and small molecule libraries for high-throughput screening; and execute standard/routine analysis procedures and prepare preliminary reports of large data sets.  The candidate will also work with the Directors to strategically develop new screening assays, screening platforms, libraries, or data analysis pipelines.  Additional responsibilities will include maintaining articulate documentation of daily tasks and maintenance of the laboratory’s databases and inventory (i.e. supplies, reagents, and equipment).

Responsibilities will include, but not limited to:

  • Operation of laboratory robotics for high-throughput screening
  • Execution of experiments to optimize and validate  assays for high-throughput screening
  • Data analysis and preparation of preliminary reports for review by Directors
  • Maintenance of siRNA, shRNA, cDNA, and small molecule libraries

Qualifications:

A highly motivated individual with a Bachelor’s degree and 2 years of experience or equivalent combinations of education and experience. The ideal candidate will have strong organizational skills, effective communication skills, the ability to problem-solve, work independently, and work in a team environment.

Job Location - City, State

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$36,401.00 - $65,521.00

Affirmative Action Statement 

Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements 

Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

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