University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Job Description Summary

The Gene Therapy Program (GTP) is entering a new era of unprecedented opportunity with the great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases.

The laboratory of Dr. Jim Wilson, at GTP of the University of Pennsylvania, has been a leader in the development of innovative vector technology for close to three decades. We have emerged as the “go-to” organization for public and private partners, who want to participate in the gene therapy space. Currently, we are positioned to lead another round of vector innovation and establish pre-clinical and clinical proof-of-concept in therapeutic applications of in-vivo genome editing.

Continuation of all GTP positions is contingent upon funding.

Job Description

Our Vector Core is a state-of-the-art facility which provides vector-related materials and services in support of basic and translational research worldwide, producing vectors in support of IND-enabling research, conduct GLP assays, oversee CMO's in vector production and is expanding to conduct state-of-the art process development.

We are looking for a Assay Development Associate Scientist, to support the characterization and/or release of vector products for research, IND-enabling studies and phase I human clinical trials.

As Analytical Development Associate Scientist, you will execute assay development/optimization for common molecular and cell based assays. Applying scientific knowledge, critical thinking, and problem-solving abilities, you will troubleshoot and refine methods and assays, taking research grade assays and develop them into our standardized assay format, following established protocols and novel methods. You will also assist Assist with assay qualification and validation as well as assist with the technology transfer of new/update assays to QC testing groups.

You will work both  independently and as part of a team to accomplish project goals within specified timelines. Successful candidates will have a familiarity with molecular, cell-based, and plaque assays as well as mammalian cell culture.

Qualifications:

• BS Degree in Biochemistry, Biology, or related disciplines + 5 to 7 years of relevant experience.
• Must have experience in mammalian cell culture, molecular, cell-based, and plaque assays.
• Knowledge of assay development concepts for biological testing helpful
• Ability to operate in a fast-paced, multi-disciplinary environment.
• Must be an independent thinker, meticulous, detail oriented, and analytical.
• Must be highly motivated, have excellent organizational, communication and interpersonal skills.
• Must be able to work independently and as part of a multi-disciplinary team.

Job Location - City, State
Philadelphia, Pennsylvania

Department / School
Perelman School of Medicine

Pay Range
$50,684.00 - $91,232.00

Affirmative Action Statement

Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements

Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.