Research Specialist A, Pulmonary, Allergy and Critical Care Department

Pennsylvania, United States
24 Nov 2020
End of advertisement period
24 Jan 2021
Contract Type
Full Time

University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Job Description Summary

The Research Specialist A will be focused on our project to develop a nanomedicine-based treatment for the acute lung disease ARDS, which afflicts 190,000 US patients/year, has a 40% mortality rate, and no approved drugs.

Plans and conducts basic experiments to meet research project objectives, with close supervision. Assists in performing laboratory experiments and clinical studies for product or material formulation and development. Daily management of laboratory tool, documentations and processes to ensure regulatory compliance and timely completion of project/program deliverables. Closely collaborates with Senior Research Specialists and Principal Investigator (PI) on experimental/clinical work set ups in accordance to established protocols.

Position contingent upon funding.

Job Description

The Research Specialist A will be focused on our project to develop a nanomedicine-based treatment for the acute lung disease ARDS, which afflicts 190,000 US patients/year, has a 40% mortality rate, and no approved drugs. We started this project purely in academia, won the award for top new technology from ATS (the main lung research society), and now the project is being funded and conducted in conjunction with a pharmaceutical company to further the development of this treatment. Thus, the project provides a good opportunity to work on developing a new therapy, with experience both in academia and with the pharmaceutical company with which we are collaborating.

The Research Specialist A will perform a broad range of experiments in nanomedicine, pharmacology, and mouse work. The methods will include: producing and characterizing drug-loaded nanoparticles; pharmacological biodistribution experiments (injecting mice with drugs and harvesting organs to determine drug distribution); and the most frequent technique for the Research Specialist A will be injecting our nanomedicines into mouse models of ARDS, such as intra-tracheal LPS followed, by organ harvest within 72 hours to determine ARDS phenotypes and drug side effects.

The Principal Investigator designs the experiments, but the applicant will be expected to troubleshoot these procedures as needed. The applicant will also keep accurate notebooks, perform data analysis, and assist in publication preparation. Additional duties will include assisting in experimental design, and participating in general laboratory activities such as lab meetings, ordering, and maintenance.


Bachelor's Degree with 0-1 year of related experience in research and clinical study methodologies or an equivalent combination of education and experience required.

Working Conditions

Office, Library, Computer Room; Requires extensive safety

Physical Effort

Typically sitting at a desk or table; Occasional lifting 25 lb. or less

Job Location - City, State

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$35,568.00 - $57,600.00

Affirmative Action Statement 

Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements 

Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.