Research Specialist A, Pulmonary, Allergy and Critical Care Department
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Job Description Summary
The Research Specialist A will be focused on our project to develop a nanomedicine-based treatment for the acute lung disease ARDS, which afflicts 190,000 US patients/year, has a 40% mortality rate, and no approved drugs.
Plans and conducts basic experiments to meet research project objectives, with close supervision. Assists in performing laboratory experiments and clinical studies for product or material formulation and development. Daily management of laboratory tool, documentations and processes to ensure regulatory compliance and timely completion of project/program deliverables. Closely collaborates with Senior Research Specialists and Principal Investigator (PI) on experimental/clinical work set ups in accordance to established protocols.
Position contingent upon funding.
The Research Specialist A will be focused on our project to develop a nanomedicine-based treatment for the acute lung disease ARDS, which afflicts 190,000 US patients/year, has a 40% mortality rate, and no approved drugs. We started this project purely in academia, won the award for top new technology from ATS (the main lung research society), and now the project is being funded and conducted in conjunction with a pharmaceutical company to further the development of this treatment. Thus, the project provides a good opportunity to work on developing a new therapy, with experience both in academia and with the pharmaceutical company with which we are collaborating.
The Research Specialist A will perform a broad range of experiments in nanomedicine, pharmacology, and mouse work. The methods will include: producing and characterizing drug-loaded nanoparticles; pharmacological biodistribution experiments (injecting mice with drugs and harvesting organs to determine drug distribution); and the most frequent technique for the Research Specialist A will be injecting our nanomedicines into mouse models of ARDS, such as intra-tracheal LPS followed, by organ harvest within 72 hours to determine ARDS phenotypes and drug side effects.
The Principal Investigator designs the experiments, but the applicant will be expected to troubleshoot these procedures as needed. The applicant will also keep accurate notebooks, perform data analysis, and assist in publication preparation. Additional duties will include assisting in experimental design, and participating in general laboratory activities such as lab meetings, ordering, and maintenance.
Bachelor's Degree with 0-1 year of related experience in research and clinical study methodologies or an equivalent combination of education and experience required.
Office, Library, Computer Room; Requires extensive safety
Typically sitting at a desk or table; Occasional lifting 25 lb. or less
Job Location - City, State
Department / School
Perelman School of Medicine
$35,568.00 - $57,600.00
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