The Vasiliou Laboratory at the Yale School of Public Health seeks a qualified Lab Associate to support our NIAAA-funded R42 Center by generating and maintaining transgenic mouse models for alcohol-associated diseases. A variety of technical laboratory procedures are required for designing and implementing procedures to develop and maintain these mouse lines.
- Set-up colony of gene targeted / transgenic mice, work with the PI on designing and implementing procedures to develop and maintain transgenic mouse models for alcohol-associated diseases mouse lines.
- Ability to perform mouse/animal surgeries including; embryo transfer, cesarean section and fostering.
- Ability to perform mouse sperm and embryo cryopreservation; recovery and rederivation of mouse strains using invitro fertilization.
- Breed and maintain the transgenic knockout mouse colonies.
- Ensure that mouse colonies are properly maintained including analysis and presentation of the proper genotype.
- Communicate with and interact with internal contacts including the PI, research assistants, graduate students, Radiation Safety and Biological Safety officers, and Animal Care personnel to discuss and evaluate research results and to ensure the smooth and safe operation of the laboratory.
- Communicate with external contacts such as researchers at other institutions, staff at biotechnology and reagents companies to consult on research methods and the animal models in the PIs laboratory.
1. Designs, plans, implements and evaluates complex multifaceted research projects/systems, including method development, adaptation and validation. 2. Collaborates with PI to define research endeavors and the development of research hypothesis and approach. 3. Solves complex methodology, protocol, procedural and research problems through design of techniques, procedures and policies that will achieve research goals. 4. Develops long range plans for supplies and equipment to ensure smooth operation of laboratory. 5. Investigates, analyzes and evaluates complex data, data collection systems and methods to reach scientific conclusions and ensures the integrity of research data. 6. Collaborates with PI to coordinate major lab renovations working with Facilities, Health and Safety, and Purchasing to ensure deadlines, safety standards and purchases are according to plans and within budgets. 7. Prepares scientific reports and papers for research proposals and published reports. 8. May perform other duties as assigned.
Required Education and Experience
Master’s Degree in a scientific discipline and three years of experience or an equivalent combination of education and experience.
Required Skill/Ability 1:
Ability to build gene targeted/transgenic colonies (including, multiple gene knockouts), and performing mouse/animal surgeries including embryo transfer, cesarean section and fostering, as well as mouse sperm and embryo cryopreservation, and developing multiple gene knockouts by cross breeding animal colonies.
Required Skill/Ability 2:
Well-trained in safe lab practices.
Required Skill/Ability 3:
Effective communicator with the ability to work alone or within a group.
Weekend Hours Required?
Evening Hours Required?
Background Check Requirements
All candidates for employment will be subject to pre-employment background screening for this position, which may include motor vehicle, DOT certification, drug testing and credit checks based on the position description and job requirements. All offers are contingent upon the successful completion of the background check. Please visit www.yale.edu/hronline/careers/screening/faqs.html for additional information on the background check requirements and process.
The intent of this job description is to provide a representative summary of the essential functions that will be required of the position and should not be construed as a declaration of specific duties and responsibilities of the particular position. Employees will be assigned specific job-related duties through their hiring departments.
Affirmative Action Statement:
Yale University considers applicants for employment without regard to, and does not discriminate on the basis of, an individual’s sex, race, color, religion, age, disability, status as a veteran, or national or ethnic origin; nor does Yale discriminate on the basis of sexual orientation or gender identity or expression. Title IX of the Education Amendments of 1972 protects people from sex discrimination in educational programs and activities at institutions that receive federal financial assistance. Questions regarding Title IX may be referred to the University’s Title IX Coordinator, at TitleIX@yale.edu, or to the U.S. Department of Education, Office for Civil Rights, 8th Floor, Five Post Office Square, Boston MA 02109-3921. Telephone: 617.289.0111, Fax: 617.289.0150, TDD: 800.877.8339, or Email: firstname.lastname@example.org.
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