Life Science Research Professional 1

Location
California, United States
Posted
22 Oct 2020
End of advertisement period
21 Dec 2020
Ref
87517
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Permanent
Hours
Full Time

The Gifford lab in the Departments of Pediatrics and Genetics, and the BASE Institute is seeking a highly motivated Life Science Research Professional 1 to join us in our study of the complex genetic and molecular mechanisms involved in cardiovascular development and disease.

The ultimate goal of our lab is to make precision medicine a reality for cardiovascular disease patients. We use pluripotent stem cell and animal models to define the genes and regulatory elements necessary for cell fate decisions, and to probe how variation in these sequences can lead to congenital heart disease. Experimental approaches utilized include various RNA-sequencing modalities (e.g. single-cell, nascent RNA), ChIP-sequencing, chromatin accessibility measurements (e.g. ATAC-sequencing) and high-throughput CRISPR screens. Integrative analyses are performed using cutting edge advances in machine learning to reveal disease-causing variants and mechanisms. We work closely with physicians to ensure our experimental plans will solve critical problems faced by patients.

We are seeking a creative, driven, organized individual to aid in the design and implementation of these experiments. The LSRP1 will collaborate with the other team members to develop protocols, perform experiments, and evaluate and interpret results. 

The candidate for this position should have experience with standard molecular biology techniques and mammalian cell culture; excellent communication, organization, and time management skills; and the ability to think creatively to solve problems.

Duties include:

  • Work collaboratively with team members to develop, design, and carry out experiments that are essential to the group’s collective success
  • Optimize and apply functional genomics technologies (e.g. RNA-seq, ChIP-seq, ATAC-seq)
  • Manage mouse colony
  • Interpret experimental results; document, summarize and present findings in individual and group meetings
  • Maintain a detailed organizational plan and record to ensure successful and timely completion of required tasks
  • Contribute to generation of protocols and publications

*- Other duties may also be assigneddThe Gifford lab in the Departments of Pediatrics and Genetics, and the BASE Institute is seeking a highly motivated Life Science Research Professional 1 to join us in our study of the complex genetic and molecular mechanisms involved in cardiovascular development and disease.

The ultimate goal of our lab is to make precision medicine a reality for cardiovascular disease patients. We use pluripotent stem cell and animal models to define the genes and regulatory elements necessary for cell fate decisions, and to probe how variation in these sequences can lead to congenital heart disease. Experimental approaches utilized include various RNA-sequencing modalities (e.g. single-cell, nascent RNA), ChIP-sequencing, chromatin accessibility measurements (e.g. ATAC-sequencing) and high-throughput CRISPR screens. Integrative analyses are performed using cutting edge advances in machine learning to reveal disease-causing variants and mechanisms. We work closely with physicians to ensure our experimental plans will solve critical problems faced by patients.

We are seeking a creative, driven, organized individual to aid in the design and implementation of these experiments. The LSRP1 will collaborate with the other team members to develop protocols, perform experiments, and evaluate and interpret results. 

The candidate for this position should have experience with standard molecular biology techniques and mammalian cell culture; excellent communication, organization, and time management skills; and the ability to think creatively to solve problems.

Duties include:

  • Work collaboratively with team members to develop, design, and carry out experiments that are essential to the group’s collective success
  • Optimize and apply functional genomics technologies (e.g. RNA-seq, ChIP-seq, ATAC-seq)
  • Manage mouse colony
  • Interpret experimental results; document, summarize and present findings in individual and group meetings
  • Maintain a detailed organizational plan and record to ensure successful and timely completion of required tasks
  • Contribute to generation of protocols and publications

*- Other duties may also be assignedd

DESIRED QUALIFICATIONS:

  •  Degree in biology or related field. Highly motivated candidates of all levels are encouraged to apply.
  • 2+ years of experience in a research laboratory
  • Experience with standard molecular biology techniques and mammalian cell culture
  • Strong technical knowledge and experience with molecular biology

EDUCATION & EXPERIENCE (REQUIRED):

Bachelor's degree in related scientific field.

KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):

  • General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
  • Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
  • Ability to maintain detailed records of experiments and outcomes.
  • General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
  • Ability to work under deadlines with general guidance.
  • Excellent organizational skills and demonstrated ability to accurately complete detailed work.

PHYSICAL REQUIREMENTS*:

  • Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
  • Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
  • Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
  • Must have correctible vision to perform duties of the job.
  • Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
  • Ability to lift heavy objects weighing up to 50 pounds.
  • Ability to work in a dusty, dirty, and odorous environment.
  • Position may require repetitive motion.

*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

WORKING CONDITIONS:

  • May require working in close proximity to blood borne pathogens.
  • May require work in an environment where animals are used for teaching and research.
  • Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
  • Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
  • May require extended or unusual work hours based on research requirements and business needs.

Add or subtract physical requirements based on the requirements of your specific job. (remove this statement for posting)

Additional Information

  • Schedule: Full-time
  • Job Code: 4945
  • Employee Status: Regular
  • Grade: E
  • Department URL: http://pediatrics.stanford.edu/
  • Requisition ID: 87517

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