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Researcher in Alzheimer disease mechanisms

Employer
KAROLINSKA INSTITUTE
Location
Stockholm (SE)
Closing date
3 Nov 2020

Researcher in Alzheimer disease mechanisms

Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatric

The Department of Neurobiology, Care Sciences and Society (NVS) conducts world leading research in aging, dementia, epidemiology and care sciences. This research extends from basic molecular and cell levels to clinical research and societal studies. NVS educates almost a third of KI students at basic and advanced levels. The Department has approximately 450 employees and a revenue 2018 of 490 million SEK. It comprises seven divisions, located at Campus Flemingsberg and Campus Solna. 

The Division of Neurogeriatric consists of about 85 employees. The division conducts experimental and translational research related primarily to Alzheimer's disease and other neurodegenerative diseases, but also more general molecular mechanisms with biomedical relevance are studied, in BioClinicum, KI Campus Solna and Neo, KI Campus Flemingsberg.

Do you want to contribute to top quality medical research?

Your mission
The position is for one year in the group of Per Nillsson. The lab of Per Nilsson is focusing on preclinical research on Alzheimer’s disease. Alzheimer’s disease is characterized by accumulation of amyloid β peptide (Aβ) into extracellular Aβ plaques and this is one of the drivers of the disease. Therefore, it is important to understand the generation of Aβ. To do so we use Alzheimer mouse models which exhibit Aβ pathology. The candidate will explore molecular entities involved in Aβ generation of Aβ including the enzyme Sppl2b. The project also involves development of potential treatments using biocapsule delivery device to administer biological compounds to the brain to treat AD symptoms in the Alzheimer mouse models.

Your profile
A person is eligible to be appointed Researcher if he or she has been awarded a Degree of Doctor or has achieved the corresponding scientific competence, as well as documented research after publicly defending his or her doctoral thesis corresponding to qualification as Assistant professor. The applicant needs to have good communicative capabilities since the work is collaborative. Good ability to speak and write English is also a requirement. A strong scientific drive is expected, documented with a publication record. The successful applicant should have extensive experiences and practical skills from research animal work including animal behavior assessing cognition and memory, brain surgery in mice as well as cell-and molecular biology techniques such as, immunohistochemistry and regular protein analysis methods. Previous research experience from neurodegenerative diseases/neuroscience and working with mouse models of Alzheimer’s disease is a merit.

Bases os assessment
We stress research expertise when assessing applicants, which includes both practical and theoretical knowledge in neuroscience and Alzheimer’s disease.

What do we offer?
Karolinska Institutet is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles employees to several benefits such as extended holiday and a generous occupational pension. Employees also have free access to our modern gym and receive reimbursements for medical care.


Location: BioClinicum, Karolinska Institutet, Solna Campus

Read more about research at The Divition of Neurogeriatrics here.

Application
An application must contain the following documents in English: Resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.

Welcome to apply at the latest November 3rd 2020. 

The application is to be submitted through the Varbi recruitment system.  

Permanent position are initiated by a six months trial period.

Want to make a difference? Join us and contribute to better health for all 

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