Senior Clinical Research Manager

London (GB)
£46,292 - £54,534 per annum inclusive of London Weighting Allowance
15 Oct 2020
End of advertisement period
22 Oct 2020
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Fixed Term
Full Time

This post will involve coordination of all activities linked to the COVID Symptoms Study Research Platform and Biobank, which is the research wing of the COVID Symptom Study smartphone-based application.  The aim is to rapidly assist health planners during the pandemic using data on over 4 million UK study participants including over 1 million COVID-19 tests. The App has already provided critical insight on the spread of COVID-19 in the country to inform government policy; developed an algorithm to predict COVID-19 without a test and provided a clinical research tool to better understand the progression of the disease.

This post holder will manage the next step to extend the impact of the COVID Symptom Study (CSS) for international research, health care services and the participants themselves, joining an experienced team with expertise in population studies, detailed biological analysis and data science. 

The Senior Clinical Research Manager will implement reporting and monitoring systems to meet deadlines for deliverables and milestones within the different projects and be actively involved in the set up and quality assurance of sample and collaborations databases.

The Senior Clinical Research Manager will be responsible for:

  • Receiving and triaging applications for collaborations, liaising with collaborators and stakeholders, and presenting to the CSS Management Board.

  • Actioning collaboration liaison with science team and collaborators to select relevant recruiting lists. 

  • Drafting participant facing materials to communicate invites to satellite studies approved by the CSS Management Board, to maximise recruitment.

  • Liaising with Zoe Global for recruitment to studies, and communication of results to study participants.

  • Day to day line management of a Clinical Operations Assistant responsible for recruiting patients, obtaining consent and sample collection for the CSS Biobank.

  • Managing administration for the study, and actively contributing to the research planning and development in partnership with Principal Investigators, Executive and Steering Groups and Study Teams.

  • Being a key liaison with all university departments, relevant ethics and R&D committees, funding bodies etc.

  • Ensuring all necessary approvals are in place, recruiting sites are initiated, staff are appropriately trained, and recruitment is maximised across all sites ensuring timely recruitment of study participants into studies.

This is full-time, fixed-term contract for 12 months.

Key responsibilities

Research Platform and Biobank Management:

  • To be responsible for the day-to-day co-ordination of the COVID Symptom Study Research Platform and Biobank, ensuring that milestones and deliverables are on time and to budget.

  • To co-ordinate the smooth running of work assigned to other staff involved with the project, including staff at Department of Twin Research (DTR) skilled in managing a Biobank.

  • To oversee the recruitment of data collection and sample ascertainment for study participants in the COVID Symptoms Study Research Platform and Biobank at all sites, facilitating timely recruitment.

  • To fill out clinical report forms and enter these into an electronic database (e.g. EDGE) which must be monitored weekly.

  • To ensure that the necessary supplies and equipment for the study are in stock and in working order.

  • To line manage junior clinical staff aligned to the project.

  • To track progress as relates to tasks, deliverables and milestones.

  • To be involved with reporting and presentation of the research platform’s activities and strategies.

  • To be actively involved in the quality control of the phenotypic data relating to the project.

  • To keep up to date with recent COVID research relevant to the biobank, especially on Long COVID.

  • To attend multi-disciplinary and departmental project meetings and other meetings as required.

  • To maintain confidentiality of information about volunteers, staff and other departmental business in accordance with the Data Protection Act of 2018 and GDPR.

Communication & networking:

  • To work closely with ZOE COVID Symptoms Study Head of Product to develop and engage a participant panel to create and pilot new surveys and communication materials about the study findings, including on a personal level.

  • To develop a targeted communication and dissemination strategy which will involve e-newsletters, multi-media presentations at conferences, marketing materials in collaboration with ZOE health data science company.

Decision making, planning & problem solving:

  • To work independently to solve problems and resolve standard day-to-day and/or predictable problems.

  • To lead on the participant engagement devising new engagement strategies for CSS study volunteers.

  • To summarise volunteer feedback to identify areas of quality improvement.

  • To set up and coordinate a CSS Public and Participant Involvement (PPI) group.

  • To lead on KCL side for strategy and design of attrition and retention projects for the CSS in collaboration with ZOE Global.

  • To contribute to questionnaire development or research that needs communications expertise and input.

  • To liaise with cross-cohort engagement teams to deliver engagement strategies with other national and international groups working on COVID research, not limited to the Wellcome LPS and COVID Hub at HDRUK.

  • To lead on execution of issues relating to the COVID Symptom Study Research Platform, ensuring that they are implemented and administered effectively and resolve any problems which arise during the project.

  • To plan and prioritise a varied workload to meet deadlines in an efficient and effective manner.

  • To be integral to the IT, lab, Clinical and admin teams in ensuring all aspects of the CSS Biobank are running smoothly and be responsible for resolving issues of service delivery of the study.

Service delivery:

  • To plan, organise and set up regular project meetings, including but not limited to the COVIDX science meetings, and Management Group meeting, ensuring accurate minutes are kept and distributed.

  • To set up and manage the CSS Data access committee, involving study PIs, key professional staff and stakeholders.

  • To respond to requests for information in accordance with the project outline.

  • To be responsible for compilation of materials and writing all reports to meet milestones required by the funders.

  • To participate in the analysis of the data and writing grants, papers and abstracts.

  • To coordinate and draw up reports for PIs, project leads and funding bodies.

  • To organise meetings, face to face meetings and teleconferences with project members and collaborators.

Analysis & research:

  • To write, maintain and distribute reports as required to support the requirement of the projects.

  • To collate all relevant reporting information as well as other information being made available during the life of the project and disseminate it to the relevant bodies.

  • To keep up to date with new research relating to the ongoing programme of research in the DTR.

Teamwork, teaching & learning support:

  • To be responsible for managing the workload of Clinical Research Support Assistant and other project members within the department to enable them to meet deliverables efficiently and develop their knowledge and skills.

  • To identify training needs of staff within the department and sharing of knowledge by setting up relevant workshop training programmes.

  • To attend and contribute, via presentations, to relevant departmental meetings to ensure feedback on projects are disseminated to all other staff in the department.

  • To demonstrate a willingness to develop personal objectives via regular appraisals with their manager and to undertake appropriate training courses and attend relevant events and conferences.

Sensory/physical demands & work environment:

  • To carry out tasks that require the learning of certain skills.

  • To be aware of the risks in the work environment.

  • The post holder will have extended computer monitor use and will need to maintain high levels of concentration and mental agility at all times.

  • Attention to detail and accuracy are essential.

  • Must be able to demonstrate tact, diplomacy and sensitivity in resolving issues.

Pastoral care:

  • To show consideration to others at all times and assist with the handling of sensitive issues and complaints.

  • To maintain confidentiality of information about volunteers, staff and other Department Business in accordance with the relevant regulation.

  • To positively support equality of opportunity and equity of treatment to colleagues and students in accordance with the King’s Equal Opportunities Policy.

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.

Skills, knowledge, and experience

Essential criteria

  • MSc degree (life science/biological), or equivalent certification in a related allied health profession (e.g., nursing)

  • Knowledge of epidemiology/clinical trials • Excellent organisational skills – planning, prioritising and problem solving, with a keen eye for detail

  • Thoroughly computer literate and experienced in the use of Microsoft applications and clinical trial software

  • Ability to work as part of a multidisciplinary team

  • Knowledge of the quality assurance of clinical visit notes/paperwork and databases

  • Experience of co-ordinating highly complex research projects or clinical trials • Ability to handle confidential data safely

  • Highly self-motivated and hard working

  • Ability to work to own initiatives as well as being part of a team and prioritise workload to meet deadlines and targets

Desirable criteria

  • Project Management qualification

  • Experience of statistical analysis using packages

Further information

This post is subject to Disclosure and Barring Service and Occupational Health clearance.

This advertisement does not meet the requirements for a Certificate of Sponsorship under Home Office regulations and therefore the university will not be able to offer sponsorship for this role.