Working at MIT offers opportunities, an environment, a culture and benefits that just aren’t found together anywhere else. If you’re curious, motivated, want to be part of a unique community, and help shape the future then take a look at this opportunity.
TECHNICAL ASSOCIATE I, Biological Engineering, to join the laboratory of Professor Linda Griffith under the aegis of PhysioMimetic Research Program. A current focus of the lab is building human organs on chips with an emphasis on the gut/microbiome and other mucosal barriers, including the human female reproductive tract. These projects include clinical collaborators and human patient specimens and opportunities to work with stem cells and tissue engineering. Primary responsibilities will include maintaining and characterizing epithelial organoid cultures, preparing tissue-engineered mucosal barrier cultures using hydrogel materials developed at MIT, biochemical assays of tissue performance, data analysis and interpretation, and preparation of progress reports. Will also plan the workflow for the near term and bring up long-term issues that must be addressed by PI/ senior staff. Laboratory work includes sterile cell culture, immunohistochemistry, quantitative microscopy, ELISAs, TEER measurement analysis, and plotting of data.
REQUIRED: bachelor’s degree in bioengineering, biology, or related technical field; at least two years’ relevant experience in a research/development laboratory and at least six-months’ experience with mammalian cell culture and basic biochemical assays; ability to maintain, assemble, and operate the organ-on-chip platform; attention to detail; excellent record keeping and organizational skills; ability to carry out sterile cell culture in a biosafety cabinet; strong writing, interpersonal, communication, time-management, planning, and problem-solving skills; and proficiency with computers and Excel, Word, and PowerPoint software. Must be able to multitask; take initiative; work collaboratively and independently; and function in a fast-paced, multidisciplinary environment. Familiarity with standard biology laboratory methods including microscopy, ELISAs, spectrophotometers, and other standard analytical equipment would be ideal.
PREFERRED: comfort with mechanical devices and instrumentation. Job #18980
Experimental protocols may require working occasional night and/or weekend hours.
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