Bioinformaticians/Computational Biologists in the Laboratory of Chemical and Synthetic Systems Biology

For our growing interdisciplinary and multi-national team, we are recruiting a Bioinformatician dedicated to epigenomics next-generation sequencing (NGS) analysis, data mining and visualization, computational modeling.

To unravel the molecular circuits that underlie epigenetic gene regulation and inheritance, my laboratory combines chemical and synthetic biology manipulation of living cells with systems-level (genomic and proteomic) readouts. The successful candidate will thus participate in the experimental planning, processing, analysis, integration and publication of next- generation sequencing (NGS) data including quantitative ChIP-Seq, RNA-Seq, TT-Seq, chromosome interactome data and proteomics. The tasks will include statistical analysis, meta-analysis and data modeling. The successful candidate will work together with other members of the team and with collaborators. The ability to work independently and as part of a team is essential for this position. For more information and latest news visit http://elsaesserlab.org.

We are located at the modern Science for Life Laboratory (SciLifeLab) in Stockholm, Sweden. SciLifeLab also houses numerous state-of-the art national core facilities. We are part of the Department of Medical Biochemistry and Biophysics and the Ming Wai Lau Center for Repairative Medicine. Karolinska Institutet ranks as one of the world’s leading medical universities.

One Position Bioinformaticians/Computational Biologist

Applicants with minimally a MSc degree are welcome to apply. The ideal qualification is a PhD degree in a bioinformatics or computational field. Employment as research engineer, postdoctoral fellow or senior researcher depending on the qualification level of the applicant. For international applicants with a recent PhD degree, a 2-year postdoctoral scholarship that can be followed by further employment on the postdoctoral level of up to 4 years will typically by offered.

Appropriate to the career level, an outstanding education and productivity record is expected. Previous experience in bioinformatics documentable in publications, software packages, or thesis work are a prerequisite. Excellent command of written and spoken English.

Qualifications

Required skills of the successful candidate are:

• firm knowledge in R, Unix/Linux, Perl, Python
• robust mathematical and statistical background knowledge
• extensive experience in the analysis of next-generation sequencing data
• experience in pipeline development and data management
• knowledge of relevant biological areas (chromatin and gene expression, genetics and epigenetics)
• experience in MatLab, Mathematica or related programming languages is an advantage
• excellent knowledge in biostatistics
• experience in data genomics data mining and visualization
• proficiency in written and spoken English

It is a merit if the applicant can document the following:

• Excellent understanding of biological concepts and/or willingness to learn. Experience in working with wet lab scientists is a plus
• Excellent organizational, communication and social skills
• Excellent presentation skills

The bioinformatician will work closely with the main supervisor, Dr. Simon Elsässer, wet lab students and postdocs that generate the data, experienced bioinformaticians from the Wallenberg Bioinformatics Support Program (WABI), the Ming Wai Lau Center Bioinformatics Core.

Applications should include full CV including grades of degrees, motivation letter documenting the bioinformatics experience and stating the reasons for being interested in my lab and need to be accompanied by at least two names and contact information to request reference letter. Alternatively, you may initiate reference letters to be sent directly to references@elsaesserlab.org

Location: Solna

Application

The application is to be submitted through the Varbi recruitment system.  

Permanent position is initiated by a six months trial period.