NANYANG TECHNOLOGICAL UNIVERSITY

Research Fellow, Biochemical

Location
Singapore
Posted
06 Oct 2020
End of advertisement period
05 Nov 2020
Ref
R00001953
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Permanent
Hours
Full Time

A Research Fellow position is available in the Laboratory of Prof James Tam at the School of Biological Sciences, Nanyang Technological University.

Job Description

To participate in one or more of the following projects:

  • To work on the discovery of novel ligases by isolation
  • To work on the discovery of putative ligases by data mining and theoretical analysis
  • To work on the structure determination, biochemical characterization of peptide ligases and dynamic studies of ligases
  • To work on the design of peptide ligases
  • To work on the recombinant expression of ligases in optimization and mutagenesis
  • To work on the validation of ligases in chemical biology, protein labeling and derivatization

Job Requirements

  • PhD degree in Biosciences or related courses
  • Experience in isolation, characterization and expression of peptidyl natural products and protein ligases from medicinal plants and microbes
  • Candidates with strong analytical techniques and protein expression experience would be a plus
  • Experience in expression and mutagenesis of protein ligases with strong background in protein expression and directed evolution mutagenesis
  • Experience in assay development with strong background in molecular and cell biology in signal transduction
  • Experience in peptide chemistry with strong background in the chemical synthesis of cysteine-rich peptides and oxidative folding of disulfides
  • The position requires a highly motivated individual who has both drive and initiatives

We regret only shortlisted candidates will be notified.

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