Research Specialist D

Location
Pennsylvania, United States
Posted
24 Sep 2020
End of advertisement period
23 Nov 2020
Ref
JR00024601
Contract Type
Permanent
Hours
Full Time

University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Job Profile Title Research Specialist D

Job Description Summary

The Gene Therapy Program (GTP) is entering a new era of unprecedented opportunity with the great potential to reshape the face of medicine as we know it. Our discoveries have set the stage for successful treatments and possibly even cures for devastating genetic diseases.

The laboratory of Dr. Jim Wilson, at GTP of the University of Pennsylvania, has been a leader in the development of innovative vector technology for close to three decades. We have emerged as the “go-to” organization for public and private partners, who want to participate in the gene therapy space. Currently, we are positioned to lead another round of vector innovation and establish pre-clinical and clinical proof-of-concept in therapeutic applications of in-vivo genome editing.

Continuation of all GTP positions is contingent upon funding.

Job Description

We are currently looking for a Research Specialist D to support research translational research for neuromuscular and other CNS diseases.

As a Research Specialist D, you will create recombinant adeno-associated viral vectors (AAVs) expressing various gene products. You will examine the onset and stability of AAV-mediated transgene expression using state-of-the-art genomics techniques such as RNA-seq and STARR-seq. You will participate in the design and execution of animal studies in various animal models that include, but are not limited to, mice and non-human primates (NHP) to characterize transgene expression and safety profiles from recombinant AAVs. You will develop and conduct assays to determine the viral load in various tissues (e.g. lung, brain, liver) following viral challenge. You will computationally analyze genomics data, prepare scientific presentations, and participate in manuscript preparation. You will be able to work independently to develop collaborations with co-workers and peers at other labs and to troubleshoot as needed.

Joining GTP offers scientific professionals the unique opportunity of seeing their research go from bench to bedside and discoveries that could one day lead to cures.

Qualifications:

MA/MS and 3-5 years of relevant experience or an equivalent combination of education and experience.

Job Location - City, State Philadelphia, Pennsylvania

Department / School Perelman School of Medicine

Pay Range $50,684.00 - $91,232.00

Affirmative Action Statement

Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements

Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

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