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Research Associate

Employer
KINGS COLLEGE LONDON
Location
London (Greater) (GB)
Salary
£38,304 - £41,517 per annum, including London Weighting Allowance
Closing date
22 Oct 2020

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Academic Discipline
Biological Sciences, Life sciences
Job Type
Research Related, Research Associate
Contract Type
Fixed Term
Hours
Full Time

Job Details

This position is for a talented and enthusiastic postdoctoral molecular/cell biologist or physiologist to work on a BHF Programme Grant on Redox-regulated adaptive pathways in heart failure. The project will involve the use of iPSC-derived cardiomyocytes and “engineered heart muscle (EHM)” as model systems to investigate biological mechanisms. We therefore seek to appoint an individual with a strong background in cell and molecular biology (rather than tissue engineering), e.g.cloning, viral transduction, CrispR/Cas9 approaches, immunoblotting, microscopy of tissue sections. Previous experience with iPSC-derived cardiomyocytes or EHM is highly desirable. Experience with muscle force measurements and/or the use of in vivo models of disease would be helpful.

The postholder will be part of a multi-disciplinary research grouping working on several different aspects of cardiovascular pathophysiology, with access to state-of-the-art laboratory facilities within the King’s BHF Centre of Research Excellence.

Key responsibilities

  • Develop and undertake research of high quality consistent with making a full active research contribution in line Department/Division/School research strategy
  • Manage specific pieces of activity to an agreed timeline and within a specific budget including literature reviews, data collection and analysis, report writing.
  • Attend and, as appropriate, present research findings and papers at internal academic meetings and external professional conferences, and to contribute to the internal and external visibility of the department.
  • Work as a conscientious and committed member of the team in order to achieve the aims of the projects and the primary care group.
  • Facilitate collaboration and networking which engages and supports the activities of the project
  • Participate in educational activities as appropriate to the stage of your career.
  • To be committed to your own personal career development.
  • Liaise with the administrative team for the support of the project
  • Contribute to publications arising from this project
  • Undertake any other reasonable duties that may be relevant to the role outline.

Communication & Networking:

  • Deal with routine communication using a range of media
  • Communicate complex information orally and in writing
  • Communicate material of a specialist or highly technical nature
  • Liaise with colleagues and students
  • Build internal contacts and participate in internal networks for the exchange of information and to form relationships for future collaboration
  • Join external networks to share information and identify potential sources of funds

Decision Making, Planning and Problem Solving:

  • Use new research techniques and methods
  • Identify areas for research, develop new research methods and extend the research portfolio
  • Contribute to collaborative decision making with colleagues in area of research

Service Delivery:

  • Respond to requests for information in accordance with College policies
  • Provide advice with respect to own areas of expertise
  • Set the standards of service and ensure overall quality is maintained

Analysis & Research:

  • Develop research objectives and proposals for own or joint research, with the assistance of a mentor
  • Conduct individual and collaborative research projects
  • Write up research work for publication
  • Maintain knowledge, expertise and awareness of relevant research literature by self-directed enquiry and continuing education
  • Translate knowledge of advances in the area of expertise into research activity
  • Analyse and interpret research data and draw conclusions on the outcomes

Teamwork, Teaching & Learning Support:

  • Work with colleagues on joint projects as required
  • Collaborate with academic colleagues on areas of shared research interest
  • Attend and contribute to relevant meetings
  • Contribution to the supervision or training of more junior staff and students as necessary
  • Contribution to laboratory maintenance and administration.

Pastoral Care:

  • Show consideration to others

Skills, knowledge, and experience

Essential criteria

  • PhD in a relevant biological sciences project
  • Strong background in cell/molecular biology
  • Good written presentation skills, communication skills (written & verbal), and good IT skills
  • Broad molecular biology research experience (e.g. cloning, RT-PCR)
  • Broad cell biology experience, e.g. immunoblotting, primary cell culture, confocal microscopy, immunofluorescence
  • Successful completion of research projects (published papers in high Impact Factor journals)
  • Self-motivated, able to work independently, as well as willing and able to work as part of a team
  • Commitment to continuing personal and professional development,
  • Able to carry out know/learnt techniques unsupervised, and flexible/able to change in current professional context
  • Able to plan and prioritise workload and keep clear and well-organised laboratory notes and records

Desirable criteria

  • Background in cardiovascular biology
  • Experience of working with iPS-derived cardiomyocytes or engineered heart muscle
  • Experience of working with in-vivo models of disease or gene-modification

This advertisement does meet the requirements for a Certificate of Sponsorship under Home Office regulations and therefore the university will be able to offer sponsorship for this role.

Company

King's College London is one of the top 20 universities in the world and among the oldest in England. King's has more than 27,600 students (of whom nearly 10,500 are graduate students) from some 150 countries worldwide, and some 6,800 staff.

King's has an outstanding reputation for world-class teaching and cutting-edge research. In the 2014 Research Excellence Framework (REF) King’s was ranked 6th nationally in the ‘power’ ranking, which takes into account both the quality and quantity of research activity, and 7th for quality according to Times Higher Education rankings. Eighty-four per cent of research at King’s was deemed ‘world-leading’ or ‘internationally excellent’ (3* and 4*). The university is in the top seven UK universities for research earnings and has an overall annual income of more than £684 million.

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences including international affairs. It has played a major role in many of the advances that have shaped modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar.

King's College London and Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts are part of King's Health Partners. King's Health Partners Academic Health Sciences Centre (AHSC) is a pioneering global collaboration between one of the world's leading research-led universities and three of London's most successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental health services. For more information, visit: www.kingshealthpartners.org.

King’s £600 million campaign, World questions|KING’s answers, has delivered huge global impact in areas where King’s has particular expertise. Philanthropic support has funded new research to save young lives at Evelina London Children’s Hospital; established the King’s Dickson Poon School of Law as a worldwide leader in transnational law; built a new Cancer Centre at Guy’s Hospital; allowed unique collaboration between leading neuroscientists to fast-track new treatments for Alzheimer’s, Parkinson’s, motor neurone disease, depression and schizophrenia at the new Maurice Wohl Clinical Neuroscience Institute; created the Cicely Saunders Institute: the first academic institution in the world dedicated to palliative care, and supported the King’s Sierra Leone Partnership in the Ebola crisis. Donations provide over 300 of the most promising students with scholarships and bursaries each year. More information about the campaign is available at www.kcl.ac.uk/kingsanswers.

Company info
Mini-site
KINGS COLLEGE LONDON
Telephone
+(44)02078365454
Location
STRAND
LONDON
WC2R 2LS
United Kingdom

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