Clinical Research Associate
The Clinical Research Associate will work on an exciting project funded by a prestigious MRC award. The aim of this project is to conduct a large prospective three-year longitudinal study of glaucoma patients to dissect the molecular mechanisms leading to glaucoma surgery failure, and to identify key biomarkers for clinical risk stratification and personalised glaucoma care. The Clinical Research Associate will also set up a unique Glaucoma BioResource of RNA, DNA and tissue samples from glaucoma patients, linked to detailed longitudinal phenotyping.
The Clinical Research Associate will have the opportunity to carry out relevant translational laboratory projects in glaucoma, as well as participate in pre-clinical research projects to develop advanced therapeutics and nanomedicine in glaucoma surgery.
The post is funded for a period of 36 months and the successful candidate will be supported to register for a PhD at King's College London.
Full-time: 40 hours per week
Contract: Fixed -term for 36 month or until 31 July 2023
- Recruit and consent glaucoma patients from St Thomas' Hospital, King's College Hospital and other recruitment centres.
- Undertake detailed phenotyping, including history, examination, visual fields and OCT.
- Collect tissue samples from surgical theatre lists.
- Obtain blood samples for DNA from glaucoma patients.
- Maintain a database and organise project data of all glaucoma patients.
- Carry out relevant translational laboratory projects in glaucoma.
- Work collaboratively with other team members and clinical colleagues in all recruitment centres.
- Prepare the results of the project for publication.
- Present the results of the project at national and international meetings.
The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.
Skills, knowledge, and experience
- Undergraduate medical degree
- Completed at least two years of clinical training in ophthalmology in an approved post
- Must be registered/eligible for registration with the GMC
- Ability to perform a competent clinical ophthalmological examination, including the use of a slit-lamp and Goldmann applanation tonometry
- Ability to record and interpret standard ophthalmological investigations, such as visual fields and OCT
- Good IT and computer skills
- Should have relevant practical experience of previous clinical or laboratory research
- Should have good writing and presentation skills in English
- Commitment to high quality research
- Ability to perform technically and intellectually demanding experiments independently
- Ability to work effectively in a team and to collaborate with other research groups
- Ability to prioritise and time manage work activities, and work to deadlines
- BSc or equivalent overseas qualification
This post is subject to Disclosure and Barring Service and Occupational Health clearance.
This advertisement does meet the requirements for a Certificate of Sponsorship under Home Office regulations and therefore the university will be able to offer sponsorship for this role.