Stem cells are one of the fundamental underpinnings of tissue biology. They allow myriad tissues to be replenished by fresh cells throughout life. To preserve the regenerative capacity of the tissue, it is essential to maintain the number of stem cells. One mechanism that balances both tasks is asymmetric cell division (ACD). In ACD, each stem cell divides to generate one daughter with a stem-cell fate (self-renewal) and one daughter that differentiates.
A Techncian position is available in Dr Habib’s laboratory to study the effect of localised Wnt signals on asymmetric stem cell division and bone repair. This project combines in vitro and in vivo work (using mice as an animal model) to dissect the mechanism of asymmetric cell division and use this knowledge to engineer therapies for bone regeneration. The candidate should hold a BSc or equivalent. MSc degree is desirable. The technician will also be responsible for the maintenance of the tissue culture and the lab including placing orders for the lab. The experimental work will be carried out in King’s College London at Guy’s campus.
The successful candidate is expected to have:
1) Tissue culture work experience.
2) experience in gene cloning.
3) experience in microscopy.
4) the ability to handle mice for the required experiments
The experimental work will be carried out in King’s College London at Guy’s campus.
How to apply: In addition to your application, please submit your CV (maximum three sides of A4) and a covering letter. In your covering letter (maximum one side of A4), please summarize your previous research experience(s) and explain how do you meet the criteria above.