Research Fellow in Cardiovascular Research
Application closing date: 22/07/2020
Salary: £33,797 per annum
Job category/type: Research
We are recruiting for an experienced and highly motivated Postdoctoral scientist to join Dr. Qiaozhu Su’s research group based in the Institute for Global Food Security, School of Biological Sciences at Queen’s University Belfast. The successful candidate will undertake a senior role within a British Heart Foundation funded study focused on defining microRNA and nuclear receptor signalling in cardiomyocyte and endothelial cell remodelling in insulin resistance. This research will include the use of both vitro and in vivo models of cardiac remodelling and atherosclerosis, and the analysis of cardiac and plasma samples derived from animal models.
Applications are invited from enthusiastic, motivated and efficient individuals with a strong commitment to research. The successful candidate will have a demonstrated research background in non-coding RNAs, cardiovascular disease, or closely related fields in biomedicine with an excellent PhD degree awarded and strong publication record. The candidate should be committed to developing a dynamic, academic career in science.
The successful Research Fellow will develop, plan, and deliver cardiovascular based research under supervision within a research programme aimed at defining non-coding RNAs (I.e., microRNA and LncRNAs) and nuclear receptor signalling in cardiomyocyte and endothelial cell remodelling in insulin resistance. Techniques may include in vivo mouse models of cardiac disease including establishment of tissue specific knockout mouse models, murine echocardiography, VLDL assembly assay, aortic atherosclerotic lesion analysis, cell culture and transfection, tissue histology, aortic adhesion assay, mitochondrial integrity and dynamics, Seahorse Bioscience Analyse, Western blotting, RT-PCR, ELISA.
We offer scientific development opportunities in an international and interdisciplinary environment and support our postdoctoral fellows with an institution-based mentoring program to support career development.
The successful candidate must have:
- Have or about to obtain a relevant PhD (in molecular biology, cell biology, pharmacology or a related area of biomedicine)
- At least 3-years recent relevant research experience in non-coding RNA research, cardiovascular disease, atherosclerosis, or closely related area relevant to this project in molecular/cellular biology or biomedicine (PhD thesis must be submitted)
- Recent extensive hands-on experience in the following:
- 1. Cell culture/Western Blotting/qPCR
- 2. microRNA/long-non-coding RNA research / microRNA target prediction database
- 3. Hepatic and/or cardiac primary cell isolation / Echocardiography/Blood pressure measurement
- 4. Breeding tissue specific knockout mouse models / In vivo mouse model establishment
- Recent strong relevant publications in reputable peer-reviewed journals
The School of Biological Sciences is part of the Faculty of Medicine, Health and Life Sciences. It is made up of three research disciplines: Ecosystems Biology & Sustainability, Food Safety & Nutrition, and Microbes & Pathogen Biology.
The School aims to enhance the way we use technology in research, food security, microbiology, ecosystem biology, sustainability and many other related areas. The School provides research programmes in areas spanning from basic biochemistry with applications in e.g. cancer research, all the way to the economic evaluation of ecosystem services and the retailing of food. We host a cutting edge scientific research team and contribute to genuine new discoveries and the development of new methods of practical use. Many staff within the School are also members of the Institute for Global Food Security GRI: the Institute is ranked No 1 in the UK for research intensity in Agriculture, Veterinary and Food Sciences (REF 2014).
The Institute for Global Food Security (IGFS) is one of four Global Research Institutes at Queen's and was established to address a key, international challenge, the future of the world's food systems. Food and drink have become a global industry with many positive aspects - access, affordability, variety.
Yet that industry is also faced with a number of conundrums:
- Soon there may not be enough food to feed a growing population
- The integrity of increasingly complex food supply chains is often compromised
- Deliberate food fraud is a growing crime
- Climate change throws up complications for the future of agriculture
Queen’s University Belfast is a driver of innovation and talent based on excellence. Throughout the University, our academics collaborate across disciplines and with outside agencies and institutions on projects of world significance. We are connected and networked with strategic partnerships across the world, helping us to expand our impact on wider society locally, nationally and globally. The University is committed to attracting, retaining and developing the best global talent within an environment that enables them to realise their full potential.
We are a leader in gender equality and diversity, and are one of the UK’s most successful universities in the Athena SWAN initiative which promotes gender equality and career progression. The University holds an Athena SWAN sliver award and the School of Biological Sciences holds an Athena SWAN Gold Award in recognition of our work to support women in Science commitment and success in addressing gender equality, representation, progression and success for all our staff.
We are ranked 1st in the UK for Knowledge Transfer Partnerships, (Innovate UK) 9th in the UK for University facilities (Times Higher Education Student Experience Survey 2018) and 14th in the UK for research quality (Times and Sunday Times Good University Guide 2019).
Based in Belfast, a modern capital city, our beautiful campus is surrounded by abundant acres of parkland and is renowned as one of the safest and affordable cities in the UK. The choice of local Schools from pre-nursery upwards are some of the best available and we are immensely proud of what our city and our University will offer you.
For full job details and essential/desirable criteria please refer to the candidate information link on our website by clicking apply. You must clearly demonstrate how you meet the criteria when you submit your application. For further information or assistance contact Resourcing Team, Queen's University Belfast, BT7 1NN. Telephone (028) 9097 3044 or email on firstname.lastname@example.org
The University is committed to equality of opportunity and to selection on merit. We welcome applications from all sections of society and particularly from people with a disability.
Fixed term contract posts are available for the stated period in the first instance but, in particular circumstances, may be renewed or made permanent, subject to availability of funding.
Informal enquiries may be directed to Dr Katerina Theodoridou via email to K.Theodoridou@qub.ac.uk