Research Specialist B

Pennsylvania, United States
16 Jun 2020
End of advertisement period
16 Aug 2020
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Full Time

University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Job Description Summary

The person who fills this position will produce in vitro transcribed mRNA for vaccine and gene editing studies. They will quality check the mRNA produced by various methods. They will aid in the immunization of mouse or rabbit model systems, followed by obtaining specimens to analyze immune responses generated. They will be responsible for managing and maintaining cell lines in a cell culture lab. Methods they will use may include 17-color flow cytometry, ELISA assays, a variety of neutralization assays, and a variety of common molecular biology techniques (gel electrophoresis, Western-blot, PCR, etc.). They will work with multiple different post-docs and senior research investigators.

Job Description


  1. Produce in vitro transcribed nucleoside-modified mRNA, QC 2 (30%) *
  2. General DNA, RNA and protein work (gel electrophoresis, Western-blot, PCR) (25%) *
  3. Cell culture work (10%)*
  4. Immunization of animals, participation in in vivo experiments (15%) *
  5. Data management and presentation (5%) *
  6. Flow cytometry, ELISA, neutralization assays (10%) *
  7. Other duties and responsibilities as assigned. (5%)

Bachelor's Degree and 1 - 3 years of experience or equivalent combination of education and experience is required. Must have some laboratory experience working with molecular biology techniques. Must be willing to work with small laboratory animals. Prior experience with tissue culture work is preferred.

Position contingent upon funding

Job Location - City, State

Philadelphia, Pennsylvania

Department / School

Perelman School of Medicine

Pay Range

$36,401.00 - $65,521.00

Affirmative Action Statement

Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements

Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

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