PhD position - Inflammation and Dysmetabolism in Malaria

Leuven, Louvain (BE)
16 Jun 2020
End of advertisement period
07 Jul 2020
Contract Type
Fixed Term
Full Time


(ref. BAP-2020-450)

With > 200 million clinical cases and over 400 thousands deaths each year, malaria remains a major health problem. In our research group, we focus on malaria complications, which are the main cause of death in malaria patients and arise from complex interactions between the parasite and the host immune and vascular systems. We investigate the pathogenesis of these complications and aim to develop improved therapies. Advanced mouse models, including transgenic parasites and conditional knockout mice, are combined with clinical studies and state-of-the-art technologies, such as multicolor flow cytometry, histology and (confocal) microscopy, imaging technologies, transcriptomics and metabolomics.


Both inflammatory markers and metabolic disturbances are highly associated with severity and mortality in malaria. In this PhD project, the aim is to investigate the regulation and mechanistic link between inflammation and metabolism in malaria and to determine how dysmetabolism may aggravate severe malaria and impede efficient therapy.


  • Highly motivated to study the immunology and metabolism of a major tropical infectious disease.
  • Felasa B certificate to work with laboratory animals.
  • An excellent curriculum with a master in biomedical sciences or in biology, biotechnology, bio-engineering, medicine or pharmacy.
  • Team player, communicative, good practical lab skills, strong analytical mindset, independent and problem-solving attitude.


  • A PhD position (4 years) in a highly dynamic research group within the excellent environment of the renowned Rega Institute at the KU Leuven. Opportunity to apply for a fellowship (e.g. FWO).
  • Excellent daily guidance and training.
  • Opportunities to participate in international collaborations and national and international conferences.
  • State-of-the-art technologies and infrastructure.


For more information please contact Prof. dr. Philippe Van den Steen, tel.: +32 16 32 22 87, mail: philippe.vandensteen@kuleuven.be.

You can apply for this job no later than July 07, 2020 via the online application tool

KU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality or impairments. If you have any questions relating to accessibility or support, please contact us at diversiteit.HR@kuleuven.be.