Technical Associate, Schwarzman College of Computing
Working at MIT offers opportunities, an environment, a culture – and benefits – that just aren’t found together anywhere else. If you’re curious, motivated, want to be part of a unique community, and help shape the future – then take a look at this opportunity.
TECHNICAL ASSOCIATE I, Computer Science and Artificial Intelligence Laboratory (CSAIL), to work at the interface of computational and experimental work seeking to dissect the mechanisms underlying human disease genetics, experimentally validate and refine biological hypotheses, and generate new datasets for computational analysis. Applications include several human diseases, specifically neurodegenerative, neuropsychiatric, immune, and cancer. Will carry out molecular assays including chromatin immunoprecipitation (ChIP-seq), assay of transposase accessible chromatin (ATAC-seq), RNA sequencing (RNA-seq), and single-cell profiling (scRNA-seq and scATAC-seq). Will perform gene knockdowns and knockouts and CRISPR-Cas9 genome editing and be responsible for implementing high-level research objectives, applying advanced research practices in broad areas of assignments and related fields. Will work closely with project coordinator, research scientists, and other researchers to plan project execution, prioritize tasks, and achieve agreed-upon goals; and interact with research scientists, postdocs, and other technical associates within the Kellis lab and collaborator labs to plan out research and interpret results.
REQUIRED: B.Sc./B.A. in biology or related field; at least two years’ experience performing molecular biology and next generation sequencing experiments; strong background in genetics, molecular biology, and gene regulation; excellent interpersonal and communication skills; ability to convey information to others in a clear and concise manner and take steps to ensure understanding; and ability to identify and selects appropriate tools, data, and analysis techniques to diagnose problems and develop solutions. PREFERRED: molecular assays experience with chromatin immunoprecipitation (ChIP-seq), assay of transposase accessible chromatin (ATAC-seq), and RNA sequencing; high-throughput assay experience; and experience with perturbation assays, including gene knockdowns and knockouts, regulatory element perturbations, and genome editing. Job #18493
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