MASARYK UNIVERSITY

Postdoc Position, Department of Biology

6 days left

Location
Brno, Czech Republic
Posted
20 Jan 2020
End of advertisement period
29 Feb 2020
Ref
52452
Contract Type
Fixed Term
Hours
Full Time

POSTDOC POSITION in Identification and characterization of factors involved in meiotic DNA double strand breaks repair

Department Department of Biology – Faculty of Medicine

Deadline 29 Feb 2020

Start date March/April 2020 or upon agreement but no later than by 30th November 2020

Masaryk University, Brno, Czech Republic invites excellent scientists to apply for POSTDOC POSITION in Identification and characterization of factors involved in meiotic DNA double strand breaks repair

Description:

POSTDOC position will be available to carry on the characterization of the meiotic roles exerted by C. elegans BRC-1 in promoting DNA repair, with particular emphasis on unravelling how post-translational modifications regulate the activity of this protein. Moreover, we identified a completely uncharacterized BRC-1 paralog which might shed new light on the mode of function of BRC-1. Further, functional analysis of the PARG-BRC-1 interaction will also be performed, possibly in a shared effort between the two PhD students.

Moreover, study of PARG-1 functions during meiosis also holds a crucial interest in the lab, and we have identified an important and completely unknown involvement of this protein during gametogenesis. Deep characterization of its mode of action and identification of both interactors and putative substrates will be performed.

The successful candidate should:

  • be a researcher who has received a PhD or its equivalent within the last 7 years
  • be a researcher who has worked at least two whole years in the last three outside the territory of the Czech Republic in the field of research with a working time of at least 0.5 full-time equivalent, or who has been PhD student (or equivalent) abroad
  • have a publishing record – in the last three years at least two publication outputs registered in the Thomson Reuters Web of Science, Scopus or ERIH PLUS databases and at the same time publications such as “articles”, “books”, “book chapters”, “letters” and “reviews”.

Specific criteria can be filled, i.e.:

  • Strong background in Genetics, Molecular Biology and Biochemistry
  • Solid experience with Western Blot, PCR and Immunofluorescence is highly desirable
  • Excellent communication in English, Curiosity and enthusiasm about science are all essential skills

The application should include:

  • a CV including a summary of education and research experience, publication activity, involvement in research grants, etc.
  • a scanned copy of the PhD diploma or an official letter certifying submission of a doctoral thesis for thesis defence and the planned defence date
  • a motivation letter
  • at least two contacts for references

MU offers the opportunity to get:

  • an interesting job in a dynamically-expanding university area
  • diverse and challenging work in an excellent research environment
  • tenure track with an initial appointment for 2 years
  • a professional team and pleasant working conditions
  • interaction with leading scientists in an inspiring, internationalised environment
  • a welcoming service for the successful candidate and his/her family

Anticipated start date: The position is available from March/April 2020 or upon agreement but no later than by 30th November 2020.

The submission deadline is 29th February 2020

Please submit your application by e-mail to vrablikova@med.muni.cz

A review of applications will commence immediately after the deadline. Short-listed candidates will be invited for interview within one month of the deadline.

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