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Research Associate

Employer
KINGS COLLEGE LONDON
Location
London (Greater) (GB)
Salary
Grade 6, £38,304 per annum, inclusive of London Allowance.
Closing date
7 Jan 2020

Job Details

Informal inquiries are strongly encouraged. ciro.chiappini@kcl.ac.uk

THE ROLE

We are seeking a highly motivated and talented postdoctoral researcher for a 2 year fixed-term contract, starting March 1st, 2019, to develop nanomaterial-based gene delivery strategies for the topical treatment of genetic skin conditions. We are looking for someone with a strong experience with cloning and in vitro RNA transcription. Further, experience with in vitro and in vivo transfection optimization in hard-to-transfect cells is required. Experience with nanomaterials for drug delivery, optical microscopy and cell biology would be advantageous.

The typical candidate will have:

  • PhD in Biology, Bioengineering, Biochemistry or related field.
  • Cloning experience.
  • In vitro RNA transcription experience.
  • Gene therapy experience.
  • Evidence of productivity through high quality publications.
  • Strong work ethics.
  • Independence and team-work ability.

THE GROUP

The Nanomaterials and Biointerfaces group of Dr. Chiappini is based in the Centre for Craniofacial and Regenerative Biology at King’s College London. The group blends nanotechnology, bioengineering and cell biology to develop advanced materials for dynamic with intracellular interaction. We leverage this controlled cell interaction to engineer platforms for regenerative medicine and precision medicine. This project is in collaboration with the groups of Professor John McGrath and Professor Jakub Tolar at the University of Minnesota. For more information visit http://chiappinilab.com

THE PROJECT

This exciting project is to investigate nanomaterial-based strategies for the local targeted delivery of nucleic acids to exposed skin wounds due to genetic skin disease. The aims of the project are to identify an efficient delivery strategy to skin organoid cultures and in a murine animal model (collaboration UNM), and validate the correction of the genetic defect, alongside its effects promoting wound healing. The work follows up from two of our recent publications on nanodelivery strategies for DNA plasmids (Chiappini et al. Nature Materials 2015) and gene-therapy correction of skin diseases (Georgiadis et al. Journal of Investigative Dermatology 2016).

This post will be offered on a fixed-term contract for 2 years.


This is a full-time post.


The selection process will include a panel interview, an assessment, a presentation.


To apply, please register with the King’s College London application portal and complete your application online.

Company

King's College London is one of the top 20 universities in the world and among the oldest in England. King's has more than 27,600 students (of whom nearly 10,500 are graduate students) from some 150 countries worldwide, and some 6,800 staff.

King's has an outstanding reputation for world-class teaching and cutting-edge research. In the 2014 Research Excellence Framework (REF) King’s was ranked 6th nationally in the ‘power’ ranking, which takes into account both the quality and quantity of research activity, and 7th for quality according to Times Higher Education rankings. Eighty-four per cent of research at King’s was deemed ‘world-leading’ or ‘internationally excellent’ (3* and 4*). The university is in the top seven UK universities for research earnings and has an overall annual income of more than £684 million.

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences including international affairs. It has played a major role in many of the advances that have shaped modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar.

King's College London and Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts are part of King's Health Partners. King's Health Partners Academic Health Sciences Centre (AHSC) is a pioneering global collaboration between one of the world's leading research-led universities and three of London's most successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental health services. For more information, visit: www.kingshealthpartners.org.

King’s £600 million campaign, World questions|KING’s answers, has delivered huge global impact in areas where King’s has particular expertise. Philanthropic support has funded new research to save young lives at Evelina London Children’s Hospital; established the King’s Dickson Poon School of Law as a worldwide leader in transnational law; built a new Cancer Centre at Guy’s Hospital; allowed unique collaboration between leading neuroscientists to fast-track new treatments for Alzheimer’s, Parkinson’s, motor neurone disease, depression and schizophrenia at the new Maurice Wohl Clinical Neuroscience Institute; created the Cicely Saunders Institute: the first academic institution in the world dedicated to palliative care, and supported the King’s Sierra Leone Partnership in the Ebola crisis. Donations provide over 300 of the most promising students with scholarships and bursaries each year. More information about the campaign is available at www.kcl.ac.uk/kingsanswers.

Company info
Mini-site
KINGS COLLEGE LONDON
Telephone
+(44)02078365454
Location
STRAND
LONDON
WC2R 2LS
United Kingdom

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