We are seeking a self-motivated ambitious post-doctoral researcher to investigate gene expression from the X chromosome in the autoimmune disease, SLE. We will be testing the hypothesis, based on preliminary data, that the physiological process of X inactivation is faulty in SLE. This study will use data from full length singe cell RNA sequencing, which provides a cutting edge tool with which to examine loss of X chromosome inactivation. This is a complex analysis and the applicant must have experience of handling and interrogating NG sequencing data, preferably with experience in RNA sequencing analysis. The results of these studies have ramifications for the well known sexual dimorphism in almost all autoimmune disease, which is most marked in SLE. The post holder will work in a group that has made major contributions to the genetics and functional genomics of SLE.
This post will be offered on a fixed-term contract for up to 16 months.
This is a part-time post - 80% full time equivalent.
The selection process will include a panel interview and a presentation.
For an informal discussion to find out more about the role please contact: Professor Tim Vyse, firstname.lastname@example.org
To apply, please register with the King’s College London application portal and complete your application online.