Research Fellow, Centre for Cancer Research and Cell Biology
Application closing date 27/11/2019
Salary £33,797 per annum.
Job category/type Research
Queen's University Belfast is one of the prestigious Russell Group of UK research-intensive universities in the UK and Ireland, combining excellence in research and education with a student centred ethos, for our 24,000 students and 4,200 staff, funded through an annual turnover of some GBP 300m. As a driver of innovation and talent, based on excellence and global strategic partnerships, we offer generous employment terms and underpinned by excellent lifestyle benefits including opportunities for family friendly working and support for wellbeing.
The School of Medicine, Dentistry and Biomedical Sciences holds the prestigious Athena SWAN Silver award that is valid until November 2019.
Our five core values - Integrity, Connected, Ambition, Respect, Excellence - are shared by our staff and students, representing the expectations we have for ourselves and each other, guiding our day-to-day decisions and the way we behave as individuals in an international organisation.
The Centre for Cancer Research and Cell Biology (CCRCB) is the beating heart of a comprehensive cancer research programme in Belfast, focused on accelerating the delivery of scientific discovery to clinical application. CCRCB is the research hub of the Belfast ECMC and the Belfast Experimental Cancer Medicine Centre (ECMC), operating in partnership with the Belfast Health and Social Care Trust. Our integrated clinical and scientific programmes address clinically unmet needs. Our principal objective is to promote evidence-based, innovative clinical trials in order to underpin improved patient outcomes in high incidence solid tumours of Gastro-Intestinal, Prostatic, Breast and Ovarian origin, and in specific Blood Cancers. Our unifying research theme is to develop translational outputs, in the form of biomarkers and/or novel therapeutic strategies that enable our Centre to be at the forefront of personalised cancer medicine in these prevalent diseases.
You will support the Belfast Experimental Cancer Centre (ECMC) programme. You will be involved in the design and delivery of pre-clinical studies that will inform the development of future clinical trials and support translational research arising from ongoing trials. Utilising in vitro and in vivo colorectal and prostate cancer model systems, you will work to define optimal doses and scheduling of novel combination therapies to overcome therapeutic resistance in order to improve treatment outcomes in advanced colorectal and prostate cancer. Specifically this project will focus on overcoming resistance to apoptosis following treatment with DNA-damaging chemotherapy or radiotherapy.
The successful candidate must have:
- Have or be about obtain a PhD in cancer biology, molecular biology or a related discipline
- UK Home Office Personal Licence
- At least three years relevant research experience with publication record commensurate with experience.
- Experienced in in vitro culture models.
- Experienced in a range of molecular and cellular biology techniques, such as PCR, IHC/IF, Western blot, flow cytometry.
- Experience in working with transplant and GEMM models, and demonstrated competencies in SubQ and IP techniques.
- Experience in working with modelling radiation response in animal models.
This post is available until 30 June 2020.
Informal enquiries may be directed to Dr Emma Kerr via email to firstname.lastname@example.org