Research Fellow, The Wellcome-Wolfson Institute for Experimental Medicine

Belfast, Northern Ireland
£33,797 to £35,845 per annum.
19 Oct 2019
End of advertisement period
13 Nov 2019
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Full Time

Application closing date 13/11/2019  
Salary £33,797 to £35,845 per annum.  
Job category/type Research

Job description

Queen's University Belfast is one of the leading universities in the UK and Ireland and is a member of the Russell Group of UK research-intensive universities. Queen's combines excellence in research and education with a student centred ethos.  We have over 24,000 students, 4,200 staff and an annual turnover of some GBP 300m.  We offer generous terms and conditions of employment underpinned by excellent benefits including attractive well-being, family friendly and other lifestyle benefits.  Research staff at QUB are also entitled to up to 10 days per year to spend on activities benefiting their career development.  

Our five core values - Integrity, Connected, Ambition, Respect, Excellence - are shared by our staff and students, representing the expectations we have for ourselves and each other, guiding our day-to-day decisions and the way we behave as individuals in an international organisation. 

The Wellcome Wolfson Institute for Experimental Medicine (WWIEM) is an interdisciplinary research centre which is committed to the highest quality scientific endeavour, with over 250 basic and clinical scientists working on site.  Our mission is to understand the mechanisms of disease and use that understanding to develop innovative new treatments and therapies to improve patient outcomes. 

We are recruiting for a Research Fellow to join Dr Andriana Margariti's Stem Cell biology research team and Regenerative Medicine in vascular diseases within the WWIEM. The successful candidate will work on a BHF-funded project based on endothelial cell dysfunction and blood vessels organoids in diabetes using the remarkable technology of patient specific induced pluripotent stem cells. The underlying mechanisms of endothelial cell dysfunction and blood vessels organoids will be investigated based on RNA binding proteins and the mRNA splicing machinery. This project is employing cutting edge technologies of cell reprogramming and generation of diabetic patient specific cells. Complex in vitro and in vivo models will be used to assess and restore the function of diabetic endothelial cells in vascular repair. This project holds the potential to explore novel treatments for diabetes and development of key biomarkers.

The successful candidate must: 

  • Have or about to have a PhD in a biomedical field of laboratory-based research.
  • At least 3 years recent relevant research experience, to include:
  • - Cell culture, including experience working with stem cells 
  • - Standard molecular biology techniques (eg real time PCR, western blots, staining etc.)

Informal enquiries may be directed to Dr Sophia Kelaini via email: s.kelaini@qub.ac.uk 

Candidate Information
About the Institute
About the Group
Further information for international applicants
Note to EEA applicants on Brexit

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