Department RECETOX – Faculty of Science
Deadline 31 Oct 2019
Start date upon agreement

We are seeking a highly motivated scientist for an EU-funded postdoctoral position in protein structural biology for an experimental team at Loschmidt Laboratories, Faculty of Science, Masaryk University.

More about us on https://loschmidt.chemi.muni.cz/peg/

We conduct basic research in enzymology and fight acute stroke, cancer and Alzheimer’s disease.

JOB DESCRIPTION:

• Perform protein expression, purification and biophysical characterization
• Design and perform protein crystallization experiments
• Collect X-ray diffraction data and determine protein-ligand complex structures
• Adapt emerging structural techniques: nanocrystallography and cryo-EM
• Work in an friendly, inspiring and highly collaborative environment
• Opportunities for further training, personal growth and benefits package

PROFILE OF CANDIDATE:

• Ph.D. in structural biology, molecular biology, biochemistry or biophysics
• Experience with protein expression and purification
• Previous experience with protein structural techniques
• Experience with biophysical and biochemical protein characterization
• Willingness to learn new techniques: nanocrystallography and cryo-EM
• Ability to develop new concepts; goal-oriented and problem-solving skills
• Good proficiency in English

APPLICATIONS:

• Curriculum Vitae and motivation letter
• Two letters of recommendation
• Send your application to Jitka Sedlackova at jitkasedlackova@mail.muni.cz

SELECTED PAPERS:

• J. Am. Chem. Soc. 140: 17999, 2018   •ACS Catalysis 8: 9420, 2018
• J. Am. Chem. Soc. 137: 4988, 2015     •ACS Catalysis 6: 7597, 2016
• Chem. Rev. 113: 5871, 2013                 •Curr. Opin. Chem. Biol. 19: 8, 2014
• Angewandte Chemie 52: 1959, 2013  •Nature Chem. Biol. 10: 428, 2014