MASARYK UNIVERSITY

Postdoc, Protein Structural Biologist

Location
Brno, Czech Republic
Posted
04 Jun 2019
End of advertisement period
30 Jun 2019
Ref
47669
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Permanent
Hours
Full Time

RECETOXFaculty of Science

Deadline 30 Jun 2019

Start date upon agreement

We are seeking a highly motivated scientist for an EU-funded postdoctoral position in protein structural biology for an experimental team at Loschmidt Laboratories, Masaryk University, Brno, Czech Republic (https://loschmidt.chemi.muni.cz/peg/). We conduct basic research in enzymology and fight acute stroke, cancer and Alzheimer’s disease.

JOB DESCRIPTION:

  • Perform protein expression, purification and biophysical characterization
  • Design and perform protein crystallization experiments
  • Collect X-ray diffraction data and determine protein-ligand complex structures
  • Adapt emerging structural techniques: nanocrystallography and cryo-EM
  • Work in an friendly, inspiring and highly collaborative environment
  • Opportunities for further training, personal growth and benefits package

PROFILE OF CANDIDATE:

  • Ph.D. in structural biology, molecular biology, biochemistry or biophysics
  • Experience with protein expression and purification
  • Previous experience with protein structural techniques
  • Experience with biophysical and biochemical protein characterization
  • Willingness to learn new techniques: nanocrystallography and cryo-EM
  • Ability to develop new concepts; goal-oriented and problem-solving skills
  • Good proficiency in English

APPLICATIONS:

  • Curriculum Vitae and motivation letter
  • Two letters of recommendation
  • Send your application to Jitka Sedlackova at jitkasedlackova@mail.muni.cz

SELECTED PAPERS:

  • J. Am. Chem. Soc. 140: 17999, 2018   ACS Catalysis 8: 9420, 2018
  • J. Am. Chem. Soc. 137: 4988, 2015   ACS Catalysis 6: 7597, 2016
  • Chem. Rev. 113: 5871, 2013    Curr. Opin. Chem. Biol. 19: 8, 2014
  • Angewandte Chemie 52: 1959, 2013  Nature Chem. Biol. 10: 428, 2014

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