Research Specialist

Pennsylvania, United States
29 May 2019
End of advertisement period
29 Jul 2019
Contract Type
Fixed Term
Full Time

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

The Perelman School of Medicine at the University of Pennsylvania is the oldest and one of the finest medical schools in the United States. Penn is rich in tradition and heritage and at the same time consistently at the forefront of new developments and innovations in medical education and research. Since its founding in 1765 the School has been a strong presence in the community and prides itself on educating the leaders of tomorrow in patient care, biomedical research, and medical education.

A Research Specialist A position is available in Moiseenkova-Bell lab at Perlman School of Medicine at the University of Pennsylvania. Our laboratory studies a class of membrane proteins known as Transient Receptor Potential (TRP) ion channels. They are a distinct family of Ca2+-permeable non-selective cation channels that have been implicated in a diverse range of cellular processes, including pain and temperature sensation, neuronal development, cardiovascular and renal pathophysiology, and cancer. We utilize cryo electron microscopy (cryo-EM) to determine the structural basis of TRP channels activation, inhibition and desensitization mechanisms. Structural information on TRP channels allows to enhance our understanding of their function at the molecular level, whereby improving therapeutic strategies and drug design.

The position has two components, (1) Carrying out laboratory research experiments, and (2) Providing day-to-day laboratory support. Research activities will involve molecular biology, membrane protein biochemistry and cryo electron microscopy. Laboratory support activities will include ordering supplies, coordinating equipment repair, preparing common lab reagents and maintaining general lab operation.

A Bachelor’s Degree and 0 to 1 year of experience or an equivalent combination of education and experience required. Skill sets required are excellent written and verbal communication, self-mediated drive, and a proactive approach to daily tasks. Further, candidate qualities should include a strong motivation to learn, tendency to pay exceptional attention to detail, and the ability to multitask. Previous laboratory research experience is preferred, but not required.

Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.