Research Specialist

Pennsylvania, United States
22 May 2019
End of advertisement period
22 Jul 2019
Contract Type
Fixed Term
Full Time

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

The Perelman School of Medicine at the University of Pennsylvania is the oldest and one of the finest medical schools in the United States. Penn is rich in tradition and heritage and at the same time consistently at the forefront of new developments and innovations in medical education and research. Since its founding in 1765 the School has been a strong presence in the community and prides itself on educating the leaders of tomorrow in patient care, biomedical research, and medical education.

A position is available for a highly motivated Research Specialist B to serve as a research technician for the Castleman Disease Center at Penn (CDCP) and Fajgenbaum laboratory within the Division of Translational Medicine & Human Genetics. The CDCP was recently founded to elucidate the etiology, pathogenesis, diagnostic biomarkers, and life-saving therapeutics for Castleman disease (CD)—a group of poorly-understood and deadly inflammatory disorders—and related cytokine storm and inflammatory lymphoproliferative entities. Several projects homing in on novel insights into the etiology of and cell types, signaling pathways, and cytokines that drive CD pathogenesis as well as basic insights into human immunology are underway that need to be driven toward publication and dissemination.

The position will involve small animal breeding and husbandry, human cell culture, nucleic acid and protein extraction, western blotting, ELISA, immunohistochemistry/immunofluorescence/in situ hybridization, flow cytometry, and analysis of associated data. This is a unique opportunity to join a highly motivated, patient-focused team that works closely with international collaborators to make and publish novel discoveries that will have a significant impact on patients who have diseases with major unmet medical need. This is also an excellent opportunity for professional growth and gaining scientific experiences on a collaborative and hardworking team. The Research Specialist B will report directly to the Director of Basic & Translational Research for the Center and will be expected to participate in lab meetings, discussions, manuscript development, follow laboratory protocols and processes, and assist with experiments of other lab members. The applicant must be well organized and is expected to maintain his/her own lab notebook. Additional responsibilities will include organizing/ordering materials and reagents for the lab, dealing with vendors, and sharing lab maintenance duties with other lab members. The successful candidate should have experience working in a laboratory, preferably one focused on human immunology that performed flow cytometry, omics techniques (WES, WGS, scRNAseq, proteomics, etc.), T and B cell repertoire profiling, functional immunological assays, studies using human tissue, and/or development of experimental systems.

Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.