Lab Research Analyst I, Human Vaccine Institute

North Carolina, United States
09 May 2019
End of advertisement period
09 Jul 2019
Contract Type
Full Time

Duke Human Vaccine Institute - Admin

Job Description

Laboratory Research Analyst I

The Global Health Vaccine Accelerator Platform Antibody Dynamics team at the Duke Human Vaccine Institute is seeking a detail-oriented scientist to fulfill a key role as Research Analyst 1 to perform assays to assess the kinetics of antibody-antigen interactions in response to vaccination against malaria and other global health pathogens. The study results generated by the person in this role will inform human clinical and pre-clinical trials for vaccines. The person in this role will also play a key role in assay development and standardization and in testing feasibility of novel methods.  This person must be very organized, possess excellent communication skills, have a high level of technical precision, be interested in assay development and optimization, enjoy working in a fast-paced lab environment with multiple priorities, and be able to work well as part of a team. Job functions include:


  • Perform complex and highly technical assays in the laboratory to evaluate antibody dynamics in samples from clinical and preclinical vaccine trials.  Carefully and accurately document assay conditions, results, and quality control findings and report them promptly to meet deadlines. 
  • Play a key role in the development and standardization of new assays, participating in discussions of next steps for follow up assays and in assay design.
  • Perform bio-layer interferometry, surface plasmon resonance, and other assays in the lab to develop new methods and protocols, optimize reagents, test various conditions, and determine feasibility of assays using novel antigens. 
  • Assist with data analysis, data presentation and writing of summary, qualification and validation documents.
  • Assist the laboratory and project managers by contributing to the overall effort to streamline the workload, improve the efficiency of the Antibody Dynamics team, and contribute to the daily laboratory effort to adhere to Good Clinical Laboratory Practice (GCLP) guidelines. Assist with writing and editing Standard Operating Procedures (SOP's).
  • Maintain laboratory and associated equipment in a clean, well-ordered, and functional manner.  Keep supplies on hand with a well-planned inventory and ordering system.   
  • Maintain laboratory notebook in an orderly fashion for tracking experiments and results. Provide written updates of work each week.

Education, Skills, & Experience Preferences

  • Bachelor’s degree in Chemistry, Biochemistry, Biophysics, biological science or related field
  • Strong background in laboratory techniques with technical precision
  • Two years of research experience or equivalent combination of relevant education and research experience
  • Must be able to manage multiple and rapidly changing priorities and have the ability to quickly learn new skills
  • Must be detail-oriented and well organized with strong communication skills and the ability to work in a fast-paced interactive team environment.
    Requisition Number 401595146
    Location Durham
    Duke Entity MEDICAL CENTER
    Job Family Level 11
    Full Time / Part Time FULL TIME
    Regular / Temporary Regular
    Shift First/Day


    Minimum Qualifications


    Duke University is an Affirmative Action/Equal Opportunity Employercommitted to providing employment opportunity without regard to anindividual's age, color, disability, gender, gender expression, genderidentity, genetic information, national origin, race, religion, sex,sexual orientation, or veteran status.
    Duke aspires to create a community built on collaboration, innovation,creativity, and belonging. Our collective success depends on the robustexchange of ideas—an exchange that is best when the rich diversity ofour perspectives, backgrounds, and experiences flourishes. To achievethis exchange, it is essential that all members of the community feelsecure and welcome, that the contributions of all individuals arerespected, and that all voices are heard. All members of our communityhave a responsibility to uphold these values.
    Essential Physical Job Functions:Certain jobs at Duke University and Duke University Health System mayinclude essential job functions that require specific physical and/ormental abilities. Additional information and provision for requests forreasonable accommodation will be provided by each hiring department.



    Work requires a bachelor's degree in botany, biology, zoology,psychology or other directly related scientific field.


    Work requires two years of research experience. A related master'sdegree may offset required years of experience on a 1:1 basis, e.g., atwo year master's degree in lieu of two years of experience.OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE

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