Research Specialist B

Pennsylvania, United States
10 Apr 2019
End of advertisement period
10 Jun 2019
Contract Type
Fixed Term
Full Time

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

The Perelman School of Medicine at the University of Pennsylvania is the oldest and one of the finest medical schools in the United States. Penn is rich in tradition and heritage and at the same time consistently at the forefront of new developments and innovations in medical education and research. Since its founding in 1765 the School has been a strong presence in the community and prides itself on educating the leaders of tomorrow in patient care, biomedical research, and medical education.

We are looking for a biology major who will be available to work on autophagy inhibition in cancer. The goals of the project are to use mouse models and three dimensional culture systems to determine if inhibiting the lysosome either with drugs or genetically will enhance the efficacy of immunotherapy in melanoma. The successful candidate will work under the direct supervision of a post doctoral fellow, who will also be responsible for training the research specialist. In addition to working on this project the Research Specialist will devote 20% effort towards a number of laboratory duties that will help maintain the laboratory for all of the staff. This will include maintenance of tissue culture room, ordering, receiving and organizing laboratory supplies, maintaining spreadsheets on laboratory inventory of antibodies, cell lines and molecular biology reagents, and assisting the PI in regulatory forms for animal protocols and EHRS inspections. The Research Specialist will work under the supervision of a post doctoral fellow. He/She will initially assist the post doc and eventually become completely independent in the following: General laboratory maintenance; mouse tumor growth and treatment; cancer cell culture; note keeping; and western blotting.

Bachelor’s Degree and 1-3 years prior research experience or equivalent combination of education and experience is required. We are not looking for candidates with extensive (>6 years) prior experience. Preferred candidates will have a strong knowledge of immunology, cancer biology, or both. Preferred candidates will have experience with cell culture, western blotting and mouse models.

Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.