Life Science Research Professional
Stanford University, located in the heart of Silicon Valley, is one of the world's leading teaching and research universities. Since it's opening in 1891, Stanford has been dedicated to finding solutions to big challenges and to prepare students for leadership in a complex world. A laboratory in the Institute for Immunity, Transplantation and Infection (ITI) is seeking a highly motivated Life Science Research Professional 1 (LSRP 1) to join our team. ITI is an interdisciplinary institute and the overall goal of the lab's research is to understand how the innate immune system regulates adaptive immune responses to pathogens and harness this knowledge in the design of vaccines and therapeutics. Towards this end, we are using an integrative systems biological approach that use high throughput assays (transcriptomics, micro RNA expression, metabolomics) combined with computational approaches.
The LSRP 1 primary duty will be to perform DNA digests, genotyping using PCR, analysis via gel electrophoresis and visualization, compiling results and uploading to an on-line database system for a 50+ strain mouse colony. Other duties will include lab maintenance and to assist with maintenance of the labs extensive mouse colony as needed. In addition, the LSRP 1 will work with research personnel to ensure their research needs are met. The LSRP 1 will be expected to troubleshoot existing protocols and develop novel protocols and procedures and provide technical and scientific advice to other research personnel in lab. The position will also entail lab support tasks including maintenance of lab records and adhering to safety regulations.
- Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.
- Independently conduct experiments; maintain detailed records of experiments and outcomes.
- Tissue digestion and PCR to genotype many mouse strains, analysis of results after gel electrophoresis and visualization, compilation and entry of results in a database
- Design primers for and perform genotyping experiments.
- Interpret and analyze results.
- Based on prior results, contribute to development of new research protocols and procedures or adaptation of existing protocols.
- Work with health and safety department to ensure lab complies with regulations and all required trainings.
- Participate in multidisciplinary teams across different faculties or schools.
- Contribute to the preparation of papers for publication, especially in the results section. May contribute to publication of findings and present ongoing work and findings to colleagues at academic conferences.
- Perform general lab maintenance as needed; maintain lab stock, manage safety records, and provide general lab support as needed.
- Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.
- Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.
- Contribute to publication of findings as needed.
- Participate in the preparation of written documents, including procedures, presentations, and proposals.
- Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
- Assist with orientation and training of new staff or students on lab procedures or techniques.
*- Other duties may also be assigned
- B.S. in Molecular Biology, Genetics or similar field or a related scientific field
- Experience with PCR and gel electrophoresis
- Knowledge of basic biology and molecular biology/genetics
- Skills to coordinate activities between units and investigators, and to consult with investigators regarding their research projects.
- Some background in mammalian genetics and gene editing techniques.
- Excellent organizational and planning skills using computerized data bases for scheduling procedures, time management, data entry, graph preparation, etc.
- Ability to work efficiently within an on-line database system.
- Some prior experience working with mice
EDUCATION & EXPERIENCE (REQUIRED):
Bachelor's degree in related scientific field.
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
- General understanding of scientific principles.
- Demonstrated performance to use knowledge and skills when needed.
- Demonstrated ability to apply theoretical knowledge of science principals to problem solve work.
- Ability to maintain detailed records of experiments and outcomes.
- General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
- Ability to work under deadlines with general guidance.
- Excellent organizational skills and demonstrated ability to accurately complete detailed work.
CERTIFICATIONS & LICENSES:
- Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
- Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
- Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
- Must have correctible vision to perform duties of the job.
- Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
- Ability to lift heavy objects weighing up to 50 pounds.
- Ability to work in a dusty, dirty, and odorous environment.
- Position may require repetitive motion.
*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.
- May require working in close proximity to blood borne pathogens.
- May require work in an environment where animals are used for teaching and research.
- Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
- Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
- May require extended or unusual work hours based on research requirements and business needs.