Life Science Research Professional

California, United States
14 Jan 2019
End of advertisement period
14 Mar 2019
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Full Time

The Nancy Pritzker lab in the Department of Psychiatry seeks a Life Science Research Professional 1 to join the Malenka Lab and study how neuronal circuits in the mammalian brain control behavior. Under the supervision of the PI & Senior Postdoctoral Fellows, the LSRP will be responsible for running mouse behavioral paradigms and for conducting stereotaxic surgeries to inject viruses and implant neuronal recording and manipulation devices into the mouse brain. The LSRP will work independently and with other lab members to perform these surgeries and administer post-operative care to animals. In addition, the LSRP will be responsible for histological preparation and microscopy imaging, as well as maintenance of a subset of the Malenka mouse colony, which will require tissue collection from mice and processing of genomic DNA. 

This position requires a BA/BS degree in Neurobiology, Physiology or related field. Prefer applicants with previous laboratory experience, particularly involving mouse handling, stereotaxic surgery, and/or histological tissue preparation and microscopy. 

Specific duties include:

  • Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory. 
  • Independently conduct experiments; maintain detailed records of experiments and outcomes. 
  • Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.
  • Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research. 
  • Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals. 
  • Help with general lab maintenance as needed; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
  • Assist with orientation and training of new staff or students on lab procedures or techniques.


  • Six months or more of laboratory experience
  • Knowledge of preparation of purified DNA constructs, PCR for genotyping
  • Knowledge of mouse colony maintenance or animal care
  • Knowledge of intra-cranial stereotaxic survival surgery and virus injection
  • Knowledge of intracardiac perfusion, tissue sectioning and mounting, immunohistochemistry, microscopic image acquisition


  • Bachelor's degree in related scientific field.


  • General understanding of scientific principles. Demonstrated performance to use knowledge and skills when needed.
  • Demonstrated ability to apply theoretical knowledge of science principals to problem solve work. 
  • Ability to maintain detailed records of experiments and outcomes.
  • General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
  • Ability to work under deadlines with general guidance. 
  • Excellent organizational skills and demonstrated ability to accurately complete detailed work.




  • Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds. 
  • Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts. 
  • Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls. 
  • Must have correctible vision to perform duties of the job.
  • Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
  • Ability to lift heavy objects weighing up to 50 pounds.
  • Ability to work in a dusty, dirty, and odorous environment.
  • Position may require repetitive motion.
  • Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.


  • May require working in close proximity to blood borne pathogens.
  • May require work in an environment where animals are used for teaching and research.
  • Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present. 
  • Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator. 
  • May require extended or unusual work hours based on research requirements and business needs.