Research Fellow in Cardiac Electrophysiology

Manchester, United Kingdom
£40,792 - £48,677 per annum according to experience
08 Dec 2018
End of advertisement period
08 Jan 2019
Contract Type
Fixed Term
Full Time

Location : Grafton Street, Manchester
Closing Date : 08/01/2019
Salary : £40,792 - £48,677 per annum according to experience
Employment Type : Fixed Term
Faculty / Organisational Unit : Biology, Medicine & Health
Division : Cardiovascular Sciences
Hours Per week : Full Time
Contract Duration : Fixed Term for 53 Months

You will join a team working on the cardiac conduction system of the heart jointly led by Professor Mark Boyett and Dr Halina Dobrzynski at the University of Manchester. For an informal look at the group, see Mark Boyett’s Facebook page.

The post is supported by a BHF-funded programme grant. The general aim of the project is to study the effect of heart failure, ageing and the circadian rhythm on the cardiac conduction system (sinus node, atrioventricular node and His-Purkinje system) of the heart. Dysfunction of the system in heart failure and ageing and changes in the functioning of the system from day to night are likely to be the result of changes in ion channel expression and the specific aim of the project is to investigate the mechanisms responsible for the ion channel changes with a particular emphasis on microRNAs. Finally, we will attempt to ‘repair’ the cardiac conduction system using anti-microRNAs. A range of techniques will be employed including: electrocardiography; echocardiography; measurement of expression of microRNAs and ion channels etc. using RNA-seq, qPCR, western blot and immunohistochemistry; luciferase reporter gene assays; ChIP assays; and anti-microRNAs.

The School is committed to promoting equality and diversity, including the Athena SWAN charter for promoting women’s careers in STEMM subjects (science, technology, engineering, mathematics and medicine) in higher education. The School holds a Bronze Award for their commitment to the representation of women in the workplace and we particularly welcome applications from women for this post. Appointment will always be made on merit. For further information, please visit:

“Successful candidates may be subject to pre-employment screening carried out on our behalf by a third party. The offer of employment will be dependent on the successful candidate passing that screening. Whilst you will be required to provide express consent at a later stage, by continuing with your application now you acknowledge that you are aware that such screening will take place, and agree to take part in the process.”

Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies

Enquiries about vacancy shortlisting and interviews:

Name: Mark Boyett


Tel: 0161 275 1182

General enquiries:


Tel: 0161 275 4499

Technical support:


Tel: 0161 850 2004

This vacancy will close for applications at midnight on the closing date

Further Particulars

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