Postdoctoral Researcher in Lung Cancer Tumor Signaling and Novel Therapeutics
Karolinska Institutet, Dept. of Oncology-Pathology, Lewensohn/Viktorsson
At the Department of Oncology-Pathology basic, translational and clinical research and educational activities related to cancer is carried out. Approximately 300 people from over 40 nations are currently working at the department. 37 research groups with various cancer research profiles are involved and we have around 120 PhD students. The Department of Oncology-Pathology is responsible for undergraduate courses in Pathology, Oncology and Forensic Medicine for medical students, as well as for Tumor biology courses for biomedicine students and Pathology courses for opticians.
A limited (12 months) postdoc position is available in the research group of Professor Rolf Lewensohn and Dr. Kristina Viktorsson. For more information about the research activities in the group please visit the link: https://ki.se/en/onkpat/rolf-lewensohns-group
Description of the research project/area of research
The project focus on in vitro studies in lung cancer cell lines and in vivo mice xenograft studies of lung cancer and assessment of response to growth factor receptor targeting agents, experimental therapeutics, radiation and associated kinome signaling. As postdoc in this project, you will be responsible for planning and practically conducting the in vivo xenograft studies. You will also work with cell-and molecular biology methods to explore treatment responses in lung cancer cell lines in vitro and in xenografts focusing on growth receptor and/or DNA damaging signaling in conjunction with radiotherapy.
Qualifications of the applicant
We seek a Postdoc who is highly motivated, and with a previous experience on research in vivo tumor xenograft models or similar. The candidate should be able to independently carry out in vivo xenograft experiments. Previous experience in in vivo imaging, micro surgery skills and mouse anatomy is meriting. The candidate therefore needs to have documented experience of conducting such experiments and should hold a FELASA C certificate including an updated course on Swedish legislation and ethics concerning laboratory animal science if the FELASA C is older than 2013, or Function A for Rodents and lagomorphs issued for work in Sweden.
For the in vitro part previous work experience with the following techniques are meriting: cell culture, siRNA transfection (in vitro/in vivo), clonogenic survival assays, immunofluorescence and immunohistochemistry.
As the research group has members from different parts of the world the candidate should be fluent in spoken and written English. As KI require documentation of research results electronically previous experience in working with electronic research documentation is meriting. Interpersonal skills and personal suitability is also considered important for this position.
A person is eligible for a position as Postdoctoral Researcher if he or she has obtained a PhD no more than seven years before the last date of employment as postdoc. The term can be extended under special circumstances.
Applicants that have completed their PhD degree no more than two years before the last date for applications will be given priority.
Candidates who have completed their degree earlier than this should receive equal priority if special grounds exist.
An employment application must contain the following documents in English:
- Personal letter describing interest and suitability for the announced position (no more than one page) and a summary of current work (no more than one page)
- Curriculum vitae and qualifications, presented in accordance with the Karolinska Institute qualifications portfolio (http://ki.se/meritportfolj)
- A complete list of publications
- Verifications for crediting of illness, military service, work for labour unions or student organisations, parental leave or similar circumstances
- Verification from the thesis defense committee or the equivalent (only if the thesis defense is scheduled within three months after the application deadline)
The application is to be submitted through the Varbi recruitment system.
Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences.
The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.
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Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment 2019-01-01
Number of positions 1
Working hours 100%
County Stockholms län
Reference number 2-6082/2018
Linda Gillingsjö, Research coordinator, 08 517 750 92
Med.Dr Kristina Viktorsson, Senior researcher, Kristina.email@example.com (preferred), 0701671485
Andreas Lundqvist, SACO, 08 517 76884, firstname.lastname@example.org
Helen Eriksson, OFR, 08 517 762 79
Last application date 13.Nov.2018 11:59 PM CET
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