Senior Research Investigator

Pennsylvania, United States
29 Oct 2018
End of advertisement period
29 Dec 2018
Contract Type
Fixed Term
Full Time

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

The Perelman School of Medicine at the University of Pennsylvania is the oldest and one of the finest medical schools in the United States. Penn is rich in tradition and heritage and at the same time consistently at the forefront of new developments and innovations in medical education and research. Since its founding in 1765 the School has been a strong presence in the community and prides itself on educating the leaders of tomorrow in patient care, biomedical research, and medical education.

The employee will devote his/her time conducting research in the areas of study of the tumor microenvironment and development and testing of new radiation response modifiers. This position requires the employee to be able to work with a great deal of independence in devising new areas of investigation and designing experiments. The investigator will work on delineating the role of the Unfolded Protein Response and Integrated Stress Response (UPR/ISR) in the tumor stroma (fibroblasts, immune cells, and endothelial cells) in promoting tumor growth. She/he will also engage in developing new models of proton radiation damage using different mouse strains and analyze the combined effects of radiation and UPR/ISR modifiers in the response of normal tissue to radiotherapy. Much of this work will be conducted in tumors grown in mice. Employee will work with the PI, research associates and students to coordinate and execute experiments in these areas including reviewing their experimental data and suggesting future experiments. A significant percentage of his/her time will be devoted to help the PI create grant proposals and also submit grant proposals as a co-PI

Highly advanced professional discipline. Ph.D or equivalent doctoral degree and 5 years to 7 years of experience required. A minimum of 8 years experience in dealing with animal tumor models is preferred.

Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.