Researcher Position in Skin Biology
3 days left
- Full Time
Department of Biosciences and Nutrition, Kasper (MKA)
The Department of Biosciences and Nutrition performs research and education in several areas of medical science including bioorganic chemistry, molecular endocrinology, cancer biology, functional genomics, systems biology, epigenetics, structural biochemistry, cellular virology, and nutrition. It offers an excellent international research and working environment, including around 300 scientists, students, administrative and technical personnel. The Department resides in the new biomedical research building Neo, aimed at being a creative and open environment that enables meetings, synergies, and exploration of areas of mutual interest across disciplines.
The research group of Maria Kasper at the Dept. of Biosciences and Nutrition is investigating the dynamics of stem and progenitor cells in skin – during normal physiology, wound healing and cancer initiation – using the murine skin as a model system (see lab references: Jaks et al. Nat Genet 2008, Snippert et al. Science 2010, Kasper et al, PNAS 2011, Fullgrabe et al. Stem Cell Reports 2015, Joost et al, Cell Syst 2016). To investigate the dynamics of stem/progenitor cells and their progeny in these processes we use a wide range of methods like lineage tracing and tumor mouse models, single-cell transcriptomics, FACS and advanced imaging techniques.
We are a young and dynamic research team with a well-established collaborative network. The group is located within an environment hosting a broad repertoire of technology including good access to the high-end core facilities for single-cell sequencing, mouse work, FACS sorting, and imaging (confocal, two-photon, super-resolution).
The employee will work in our multidisciplinary team of researchers including both wet-lab scientists and bioinformaticians. The main task of the successful candidate is to pursue research and research supervision in the field cutaneous wound healing and hair regeneration using animal models, high-level confocal microscopy, and single-cell RNA-sequencing. The employee is expected to analyze, discuss, interpret and integrate these data and write high-quality scientific publications. Other duties include managing mouse strain maintenance, and contributing to the supervision of postdoctoral colleagues, PhD, Master and Internship students in the group.
A person is eligible to be appointed researcher if he or she has been awarded a Degree of Doctor or has achieved the corresponding scientific competence.
We are seeking one highly motivated researcher with a good team spirit and deep curiosity for science. The ideal candidate should have a strong background in molecular biology, biomedicine or equivalent, with a keen interest in skin biology including cutaneous wound healing processes and skin cancer development and proficiency with mouse work.
Experience in working with murine skin as a model system (incl. single-cell skin dissociation, skin biopsies, and mouse surgery), molecular biology techniques, single-molecule FISH, advanced confocal microscopy, and interpreting RNA-sequencing data are a strong plus. Also a good ability to communicate in English (written and verbal) is required. A proven track record in skin biology demonstrating high-quality research in international journals is also a merit.
Bases of assessment
We stress research expertise (skills and knowledge) when assessing applicants. The applicants experience to work within skin biology and using mouse models will be assessed based on curriculum vitae and track record. Emphasis will be placed on personal suitability.
An application must contain the following documents in English:
- Curriculum vitae (max 3 pages)
- Complete list of publications
- Summary of current work (0.5-1 page)
- Contact details of two reference persons
- Ph.D. degree certificate
The application is to be submitted through the Varbi recruitment system.
At Karolinska Institutet a 6-month trial period is required for all permanent appointments.
Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences.
The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.
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Type of employment Permanent position
Contract type Full time
Number of positions 1
Working hours 100 %
County Stockholms län
Reference number 2-5198/2018
Maria Kasper, Group Leader, +46-8-524 810 29
Thomas Tinglöv, Head of Administration, +46-8-524 835 49
Henry Wölling, SEKO, +46-8-524 840 80
Birgitta Lindqvist, OFR, +46-8-524 810 28
Last application date 24.Oct.2018 11:59 PM CET