Technical Associate I, Shalek Lab

Massachusetts, United States
03 Nov 2018
End of advertisement period
03 Jan 2019
Contract Type
Full Time

Working at MIT offers opportunities, an environment, a culture – and benefits – that just aren’t found together anywhere else. If you’re curious, motivated, want to be part of a unique community, and help shape the future – then take a look at this opportunity.

TECHNICAL ASSOCIATE IInstitute for Medical Engineering and Science (IMES), to join the Shalek Lab (MIT, Broad Institute, and Ragon Institute), which specializes in leveraging novel single-cell genomic approaches to understand the behaviors of complex biological systems.  For this position, there will be a specific focus on human cancers, both liquid (e.g., leukemias and lymphomas) and solid (e.g., pancreatic ductal adenocarcinoma) tumors.  Research questions will center on drug resistance but also extend to studies of initial tumor formation and how cancer cells communicate and interact with their microenvironment. The core technique learned and applied will be Seq-Well, an in-house and customizable platform for single cell RNA-sequencing scRNA-seq library generation from thousands of cells in parallel. The project will entail careful consideration of study design, interfacing with clinical teams, fluorescence activated cell sorting (FACS), RNA-seq library preparation, next generation sequencing (NGS), data analysis in R, interpreting and contextualizing findings, and communicating results to the lab and larger community. The position offers an opportunity to gain fundamental skills working in an interdisciplinary and technologically driven environment and to gain access to the intellectual resources available across all three institutes. 

Job Requirements

REQUIRED:  bachelor’s degree, preferably with course work in (cancer) biology, immunology, chemistry, and/or genomics; at least two years of bench experience which may include undergraduate work; strong time management, communication, and problem solving skills; and the ability to learn quickly and work both independently and as part of a team.  Knowledge of R (and/or other programming languages) is desirable.  Job #16644

This is a one year position with possibility of renewal contingent on grant funding.


MIT is an equal employment opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, sex, sexual orientation, gender identity, religion, disability, age, genetic information, veteran status, ancestry, or national or ethnic origin.