Postdoctoral Researcher in Endocrine Signaling and the Regulation of Aging

4 days left

Huddinge, Sweden
10 Oct 2018
End of advertisement period
23 Oct 2018
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Full Time

Karolinska Institutet, Department of Biosciences and Nutrition, Riedel (CRI)

The Department of Biosciences and Nutrition performs research and education in several areas of medical science including bioorganic chemistry, molecular endocrinology, cancer biology, functional genomics, systems biology, epigenetics, structural biochemistry, cellular virology, and nutrition. It offers an excellent international research and working environment, including around 300 scientists, students, administrative and technical personnel. The Department resides in the new biomedical research building Neo, aimed at being a creative and open environment that enables meetings, synergies, and exploration of areas of mutual interest across disciplines.


The Integrated Cardio Metabolic Centre (ICMC) has recently been established as a research collaboration between Karolinska Institutet and the pharmaceutical company AstraZeneca to addresses a variety of strategic research areas. Out of these, our lab focuses on the study of age-related diseases. The ICMC creates a unique interface between academia and industry, provides outstanding infrastructure, and aims to develop innovative therapeutic approaches.

Research group and project

A postdoctoral position is available in the laboratory of Christian Riedel. The research group studies the molecular mechanisms that regulate aging and age-related disease, frequently using the model system C. elegans. Focus of the fully funded position is to investigate aging-regulatory endocrine signaling pathways and their downstream transcription regulatory events, with a particular interest in insulin/IGF signaling and mechanisms of its modulation.

Our research combines biochemistry (e.g. proteomics), cytology, and high-throughput sequencing techniques (e.g. ChIP-Seq and mRNA-Seq) with high-throughput genetic screening approaches (RNAi), to understand the regulation of aging at molecular and mechanistic resolution.

The position is for 1 year with the possibility of further extension.


The postdoctoral fellow is expected to play a leading role in experimental design, experimentation, analysis, and the presentation/publication of results.


The applicant should have a PhD degree in Biochemistry, Molecular Biology, Cell Biology or Molecular Genetics. He/she is expected to be a talented, highly motivated, and hardworking researcher, with a good understanding of biochemical, molecular biology, and genetic techniques. Extensive background in transcriptional regulation and aging biology is required. Likewise, we expect the applicant to have prior experience with the use of C. elegans and the genetic, RNAi screening, micro-injection, as well as lifespan analysis methods used in this system. Strong emphasis will be placed on the applicants’ scientific track-record, and his/her ability to work in a team.

The applicant should have good communication skills and be proficient in spoken and written English.

Entry requirements

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence.

Application process

An employment application must contain the following documents in English:

  1. A cover letter or letter of motivation (no more than half a page).
  2. A complete curriculum vitae, including date of the thesis defense, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work.
  3. A complete list of publications
  4. A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.

Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.

Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.

For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

Type of employment Temporary position longer than 6 months
Contract type Full time
Number of positions 1
Working hours 100 %
City Huddinge
County Stockholms län
Country Sweden
Reference number 2-5082/2018

  • Christian Riedel, PI and Senior Researcher, +46 73 670 7008
  • Thomas Tinglöv, Head of Administration, +46-8-524 835 49

Union representative

  • Henry Wölling, SEKO, +46-8-524 840 80
  • Birgitta Lindqvist, OFR, +46-8-524 810 28

Published 09.Oct.2018
Last application date 23.Oct.2018 11:59 PM CET