Life Science Research Professional
The Stanford University Protein and Nucleic Acid (PAN) Facility in the Beckman Center is seeking a full-time Life Science Research Professional 2 (LSRP2) to join our highly multidisciplinary group. The Beckman Center’s PAN facility is a multifaceted biotechnology core facility providing access to key tools and applications to researchers throughout Stanford University and other research institutions, both non-profit and biopharmaceutical.
The LSRP2 will work with Stanford researchers to plan and execute gene expression profiling and genotyping experiments as well as peptide synthesis, including purification and mass spectrometry analyses. It is expected that the individual in this position will work independently under general guidance from the supervisor and on multiple projects simultaneously. Should be receptive to instruction and possess an aptitude for learning new technologies. The LSRP must have the ability to recognize irregularities in experimental results and modify experiments as needed. Ability to adapt methods to resolve problems, improve outcomes, reduce cost and maximize success on an ongoing basis is required. The position requires an individual who is meticulous, highly organized, works efficiently, can prioritize projects and can effectively interact with a large number of diverse researchers from different scientific disciplines. The core facility environment requires this person to be proactive, co-operative, and willing to work with other facility staff as well as other Stanford investigators.
- Following established protocols, will be responsible for Nucleic Acid QC (Agilent Bioanalyzer, Fragment Analyzer), processing client RNA/DNA samples for Affymetrix microarray analysis and Next Generation Sequencing (NGS) using molecular biology procedures
- Support solid-phase peptide synthesis including HPLC purification and mass spectrometry analysis
- Implementation of NGS and microarray applications to address biological questions including their validation and optimization
- Interpret and analyze results of Nucleic Acid QC, NGS and Affymetrix microarray data often where few guidelines exist and make modifications to existing procedures and protocols
- Develop new research protocols where appropriate protocols are not described in the literature or where modification or adaptation of standard procedures and protocols is required.
- Independently conduct a portion of the research project(s).
- Make recommendations on experimental design and/or research direction to investigators
- Perform routine equipment calibration and maintenance where required
- Troubleshooting of instrument performance and ordering repairs when necessary to meet the advertised turnaround time
- Work with vendors and customers to implement technical protocols
- Directly assist members of other teams within the genomics and protein biochemistry groups so that production goals and throughput requirements are met
- Participate in multidisciplinary teams across different faculties or schools.
- Perform ongoing literature review to remain current with new procedures and related research; apply to ongoing research and development of new protocols.
- Compile and maintain accurate records of samples and archive of results in a timely fashion
- Contribute substantively to the preparation of papers for publication, especially in the results section, and to publication of findings.
- Present ongoing work to colleagues and/or academic conferences.
- Oversee supply and equipment budget under supervision of principal investigator or business manager.
- Work with health and safety department to ensure lab complies with regulations and all required trainings.
- Supervise (either formally or informally) staff or students as needed, including oversight and direction on techniques, as well as consultation on project work. Serve as a technical resource for other research staff.
- Oversee the daily activities of the laboratory including lab maintenance; maintain lab stock, manage chemical inventory and safety records, and provide general lab support as needed.
- May assist with purchasing laboratory equipment.
* Other duties may also be assigned.
- Advanced Degree in Biology, Molecular Biology, Biochemistry or related field
- Experienced in molecular biology
- Knowledge of Peptide Chemistry
- Experience in HPLC, Mass spectrometry and/or lab automation
- Highly motivated, dedicated, efficient, organized and independent
- Strong team player
- Excellent written and oral communication skills
- Possess an aptitude for learning new technologies
- Perform experiments with strong attention to detail and documentation.
EDUCATION & EXPERIENCE (REQUIRED):
Bachelor's degree in related scientific field and two years of relevant work experience; or Master’s degree in a related scientific field.
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
- Comprehensive understanding of scientific principles.
- General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
- Strong analytical skills and excellent judgment.
- Ability to maintain detailed records of experiments and outcomes.
- Ability to work under deadlines with general guidance is essential.
- Excellent organizational skills and demonstrated ability to accurately complete detailed work.
- Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
- Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
- Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
- Must have correctible vision to perform duties of the job.
- Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
- Ability to lift heavy objects weighing up to 50 pounds.
- Ability to work in a dusty, dirty, and odorous environment.
- Position may require repetitive motion.
*- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.
- May require working in close proximity to blood borne pathogens.
- May require work in an environment where animals are used for teaching and research.
- Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
- Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
- May require extended or unusual work hours based on research requirements and business needs.
- Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.
- Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for safety; communicates safety concerns; uses and promotes safe behaviors bases on training and lessons learned.
- Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University’s Administrative Guide, http://adminguide.stanford.edu.