Research Fellow in Mass Spectrometry and Ion Beam Imaging

Guildford, United Kingdom
£31,302 to £33,199 per annum
01 Oct 2018
End of advertisement period
31 Oct 2018
Academic Discipline
Physical Sciences, Chemistry
Contract Type
Fixed Term
Full Time

Department of Chemistry

Location:      Guildford
Salary:      £31,302 to £33,199 per annum
Fixed Term
Post Type:      Full Time
Closing Date:      Wednesday 31 October 2018

Do you have experience in the analysis of biological samples? Or a background in antibody labelling or mass spec? Would you be interested in piecing these things together to make an amazing new tool for bio scientists?

Proteins play a key role in the progression of many diseases, including osteoarthritis, cancer, diabetes and infectious disease such as tuberculosis. Determining the location of proteins within biological tissues is key to understanding the exact mechanisms of disease. Our group have been awarded a prestigious Fellowship award from the EPSRC ( to build a suite of analytical techniques that can drive down the dimensions for which proteins, metabolites and trace elements can be imaged in biomedical samples. The ambition is to be able to detect proteins, metabolites and trace elements at the dimensions of a cell organelle. We are looking for a postdoctoral research assistant to lead a work package, which forms one of three strands of this Fellowship project. The work package aims to develop a method for tagging antibodies with lanthanides (so that each lanthanide acts as a reporter for a different protein) and then work with our team at the National Ion Beam Centre to develop new ion beam analysis approaches to detect the tagged antibodies. MeV ion beam techniques operate at <1 micron resolution and in ambient conditions, giving the potential opportunity for multiplexed analysis of many proteins, in air and at high spatial resolution.

The ion beam centre is a national research facility funded by the EPSRC since 1979. We support £100M EPSRC grants and also have a wide industrial user base. Our users range from museums, to electronic engineers and forensic scientists. For more information, you can visit the ion beam centre website : The position is available for 2 years, but is potentially extendable for a further 3 years, subject to operational requirements. The successful candidate will not necessarily have expertise in ion beam analysis but will have expertise in some area of analytical science. We are looking for a researcher with excellent interpersonal and oral and written communication skills. The successful candidate will be able to work with our collaborators at AstraZeneca, NPL and universities in Finland, Portugal and the US with whom we will be collaborating, as well as the rest of our team.

Please direct any informal enquiries related to the project to Dr Melanie Bailey via email

For an application pack and to apply on-line please visit our website you are unable to apply on-line, please contact Ms Bianca Barrett, HR Administrator on tel: +44 (0) 1483 683419 or by email: quote Post Ref No 075518

Please note, it is University Policy to offer a starting salary equivalent to Level 3.6 (£31,302) per annum (full-time) to successful applicants who have been awarded, but are yet to receive, their PhD certificate. Once the verified original PhD certificate has been submitted to the local HR Department, the salary will be increased to Level 4.1 (£32,236) per annum (full time).

For more information and to apply online, please download the further details and click on the 'apply online' button above.

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