Research Specialist A and B

Pennsylvania United States
12 Oct 2018
End of advertisement period
12 Dec 2018
Academic Discipline
Life sciences, Veterinary Science
Contract Type
Full Time

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

The University of Pennsylvania School of Veterinary Medicine is a global leader in veterinary education, research, and clinical care. Founded in 1884, the School is a proud member of the One Health initiative, linking human, animal, and environmental health.

We are looking for research specialists related to our primary research goals that are directed toward understanding the basis of human germline development and its reconstitution in vitro. To this end, we have identified the origin and the comprehensive developmental roadmap of primordial germ cells (PGCs), the precursors both for oocytes and spermatozoa, in non-human primates (Dev Cell 2016, 39:169). Moreover, we have successfully reconstituted human primordial germ cell-like cells (hPGCLCs) in vitro from pluripotent stem cells (Cell Stem Cell 2015, 17:178). These studies provide the basis for the mechanistic dissection of the human germline specification pathway as well as the further reconstitution of human gametogenesis in vitro. Our future research plans are aimed at further maturation of hPGCLCs. For that, we also aim at understanding the molecular mechanisms of gonadogenesis and the interplay between gonadal somatic cells and germ cells, a prerequisite for the maturation of PGCs. Our studies of germ cell biology in human/non-human primates not only advance our understanding of the most fundamental part of life but also directly link to many clinical applications, such as infertility treatment and screening for the potential causes of infertility.

The holder of this position will be part of a team of researcher in the Sasaki lab within the Department of Biomedical Sciences as Research Specialist A/B. He/she will design and execute research experiments, and provide technical, research and administrative support to the principal investigator. He/she will also oversee organizational aspects of the laboratory including the coordination of technical support workers, reagents, supplies and stocks and purchase and maintenance of laboratory equipment. Motivated individuals will have the opportunity to expand his/her research portfolio by authorship or co-authorship of scientific manuscripts and will be encouraged to participate in educational/research conferences.

A Level: A Bachelor’s Degree and 0 to 1 year of experience or equivalent combination of education and experience is required.

B Level: Same as above. 1 – 2 years of experience.

Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.