Research Assistant, Department Of Biosciences

Durham, United Kingdom
Grade 6 (£26,243 - £32,236)
20 Sep 2018
End of advertisement period
19 Oct 2018
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Fixed Term
Full Time

Department : Department Of Biosciences
Position Type : Research
Grade 6 (£26,243 - £32,236)

Applications are invited for a Research Associate to work on a MRC-funded Confidence in Concept project: 
“Target validation of a novel antileishmanial”

Leishmaniasis is a Neglected Tropical Disease (NTD) caused by insect-borne Leishmania spp protozoa. With increasing cases (>12M), limited drugs and rising resistance, the development of new effective, non-toxic and affordable therapies is essential. Working with LifeArc (www.lifearc.org) we have identified a novel antileishmanial with both in vitro and in vivo activity. For development towards (pre)clinical trials the identification of the molecular target(s) is essential. In this project, the appointed researcher will generate drug resistant parasite lines and validate the molecular target(s) utilising genome sequencing coupled with metabolomic analyses. Success will facilitate entry into a hit to drug lead programme.

The post is fixed term for 12 months and the successful candidate will be working with Dr Paul Denny (PI) at Durham University and Dr Andy Merritt at LifeArc.

Closes midday on : 19-Oct-2018