Postdoctoral Associate, Synthetic Biology Center
POSTDOCTORAL ASSOCIATE, Biological Engineering-Synthetic Biology Center-Weiss Lab (2 openings), to join an interdisciplinary academic research lab which seeks to create integrated biological systems capable of autonomously performing useful tasks and to elucidate the design principles underlying the engineering of complex cellular and tissue phenotypes. Will work with a team of researchers and the lab manager to participate in a sponsored research program on new strategies for the assembly, transfection, and multiple site-specific integration of large heterologous DNA constructs into the genomes of mammalian cells used for producing therapeutic proteins at high expression levels. Responsibilities include helping design assays for genetic stability of cell clone lines and collecting data using flow cytometry, RT-qPCR, digital droplet PCR, genome walking, next-generation sequencing, ELISA and other analytic technologies, molecular cloning, mammalian cell culture, DNA transfection, lentiviral transduction, flow cytometry, and data analysis; communicating results--verbally and in writing--to team members (including industry scientists from sponsoring firm); drafting IP disclosures; making presentations to the scientific community through talks and publications; and perform other tasks as needed.
REQUIRED: Ph.D. in biological sciences, computer science, engineering, physics, math, or related field; experience in at least one of the following--mammalian cell culture, large scale DNA assembly and characterization, genetic recombination technology, next-generation sequencing, computational methods and tools for analysis, and statistics; biological experience in molecular biology, protein engineering, immunology, and/or cell biology; ability to prioritize, perform multiple tasks, and execute detailed technical protocols meticulously; strong organizational, analytical, problem-solving, and documentation skills; and ability to work collaboratively and on individual projects in a dynamic, multidisciplinary, team-oriented setting. Skills in flow cytometry and programming would be ideal.
A minimum one year commitment is required.
MIT is an equal employment opportunity employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, sex, sexual orientation, gender identity, religion, disability, age, genetic information, veteran status, ancestry, or national or ethnic origin.