MASARYK UNIVERSITY

PhD Position in Molecular Biology

Location
Brno, Czech Republic
Posted
05 Sep 2018
End of advertisement period
06 Oct 2018
Ref
42149
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Permanent
Hours
Full Time

In our lab we are interested in the study of plant hormonal signaling pathways, particularly cytokinins (CKs) in the development of model plant Arabidopsis thaliana (1-4), for more details see here. Our recent preliminary data suggest an important role for CK-regulated genes, namely EXPANSINs, in the control of cell wall (CW) properties. Besides CW critical developmental importance in plants, CW-based biomaterials are exploited in diverse human activities and have high application potential as a source of sustainable and renewable energy for the future. The aim of the project is to investigate a novel role for CKs in the regulation of CW composition and structure during CK-controlled cell differentiation. We hypothesize that CKs control cell differentiation via regulation of biomechanical properties of the CW.

As an important part of the project we will employ the CRISPR-Cas9 geneediting technology and brand-new optical method, Brillouin imaging, developed for the non-invasive measurement of biomechanical CW properties (5).

Supervisor: Dr. Marketa Samalova (SoMoPro fellow at CEITEC)

Co-supervisor: Assoc. Prof. Jan Hejátko, Ph.D.

 We offer: Experimental work on own project with the possibility of publication in top-ranked international journals, friendly lab staff, world-class equipment, attractive environment of novel university campus, help with both intellectual and practical problems, competitive salary corresponding to the work efficiency.

The position is available from September 2018.

 We expect: Highly motivated, ambitious candidates with interest in molecular biology and plants.

 Contact and further info: +420 5 4949 8476, marketa.samalova@ceitec.muni.cz

Additionally, please complete standard Application for Employment using this form:

 References

  1. Dobisova, T., et al. (2017). Plant Physiol 174, 387-404.
  2. Paniagua, C., et al. (2017). J Exp Bot.
  3. Pernisova, M., et al. (2016). New Phytol 212, 497-509.
  4. Pernisova, M., et al. (2018). Development, in press.
  5. Elsayad, K., et al. (2016). Sci Signal 9, rs5.

Information about Brno, Czech Republic

  • The capital of South Moravian Region and the second largest city in the Czech Republic with a population of almost 400,000 people
  • Modern, dynamic and fast growing centre of industry, trade, science, research and innovation with business incubators and centres of excellence in science
  • A city of universities with more than 86,000 students
  • More than 10,000 researchers; 2,200 IF publications/year; 600+ PhD graduates/year, 500 mil. EUR of R&D investment per year, more than 350 companies with in-house R&D
  • City of Gregor Mendel, the founder of genetics; the prestigious Mendel Lectures series takes place in Brno since 2003 (lectures of the world´s top scientists, including Nobel Prize winners)

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