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Research Associate

Employer
KINGS COLLEGE LONDON
Location
London (Central), London (Greater) (GB)
Salary
£38,826.00 per annum, including London Weighting Allowance
Closing date
6 Apr 2022

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Job Details

Job description

Research post in computational toxicology

We are looking to appoint an enthusiastic research assistant/post-doctoral research associate in computational toxicology to contribute to an ambitious challenge-led project co-funded by NC3Rs, AstraZeneca, Bayer AG and Unilever aimed at developing methods to replace testing of fish in the assessment of safety of chemicals to the environment. As part of regulatory approval, chemicals need to be assessed for their safety to the environment before they can be marketed, and this includes toxicity testing on fish. Our project aims to replace these tests with computational and cell culture-based methods. This post will be offered on a fixed-term contract for 6 months with possibility for reappointment for an additional 3 years.

During this initial 6 months you will contribute to mining, extracting, and analysing large-scale biological datasets to identify priority toxicity mechanisms which are specific to fish. During this phase, we will identify active pharmaceutical ingredients (APIs) for which fish are particularly sensitive. This will generate a list of prioritised mechanisms of toxicity for APIs that will be applied in the testing platform to be developed in the subsequent phase of the project.

You will be working with an internationally leading team of academics and industrial partners to guide development and deployment of new predictive computational approaches to assess safety of chemicals. The successful applicant will have a PhD or MSc with experience in informatics within a biological context and ideally good proficiency in coding. 

This post will be offered on a fixed-term contract for 6 months with possibility for reappointment for an additional 3 years 

This is a full-time post

Key responsibilities

  • Carry out (bio)informatics research relating to the NC3Rs CRACK IT DEVINA project
  • Participate in laboratory meetings 
  • Contribute to laboratory duties 

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.  

Skills, knowledge, and experience

Essential criteria  

1.       PhD or MSc 

2.       Postgraduate skills in informatics 

3.       Postgraduate skills in coding 

4.       Postgraduate level knowledge of area within Biosciences 

Desirable criteria

1.       Knowledge of toxicology and risk assessment 

2.       Knowledge of New Alternative Methodologies (NAMs) in chemical risk assessment 

3.       Knowledge of fish biochemistry and/or physiology

Company

King's College London is one of the top 20 universities in the world and among the oldest in England. King's has more than 27,600 students (of whom nearly 10,500 are graduate students) from some 150 countries worldwide, and some 6,800 staff.

King's has an outstanding reputation for world-class teaching and cutting-edge research. In the 2014 Research Excellence Framework (REF) King’s was ranked 6th nationally in the ‘power’ ranking, which takes into account both the quality and quantity of research activity, and 7th for quality according to Times Higher Education rankings. Eighty-four per cent of research at King’s was deemed ‘world-leading’ or ‘internationally excellent’ (3* and 4*). The university is in the top seven UK universities for research earnings and has an overall annual income of more than £684 million.

King's has a particularly distinguished reputation in the humanities, law, the sciences (including a wide range of health areas such as psychiatry, medicine, nursing and dentistry) and social sciences including international affairs. It has played a major role in many of the advances that have shaped modern life, such as the discovery of the structure of DNA and research that led to the development of radio, television, mobile phones and radar.

King's College London and Guy's and St Thomas', King's College Hospital and South London and Maudsley NHS Foundation Trusts are part of King's Health Partners. King's Health Partners Academic Health Sciences Centre (AHSC) is a pioneering global collaboration between one of the world's leading research-led universities and three of London's most successful NHS Foundation Trusts, including leading teaching hospitals and comprehensive mental health services. For more information, visit: www.kingshealthpartners.org.

King’s £600 million campaign, World questions|KING’s answers, has delivered huge global impact in areas where King’s has particular expertise. Philanthropic support has funded new research to save young lives at Evelina London Children’s Hospital; established the King’s Dickson Poon School of Law as a worldwide leader in transnational law; built a new Cancer Centre at Guy’s Hospital; allowed unique collaboration between leading neuroscientists to fast-track new treatments for Alzheimer’s, Parkinson’s, motor neurone disease, depression and schizophrenia at the new Maurice Wohl Clinical Neuroscience Institute; created the Cicely Saunders Institute: the first academic institution in the world dedicated to palliative care, and supported the King’s Sierra Leone Partnership in the Ebola crisis. Donations provide over 300 of the most promising students with scholarships and bursaries each year. More information about the campaign is available at www.kcl.ac.uk/kingsanswers.

Company info
Mini-site
KINGS COLLEGE LONDON
Telephone
+(44)02078365454
Location
STRAND
LONDON
WC2R 2LS
United Kingdom

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