Cancer Sciences

Location:  Southampton General Hospital
Salary:   £25,217 to £27,511
Full Time Fixed Term (12 months)
Closing Date:  Monday 10 May 2021
Interview Date:   Friday 21 May 2021
Reference:  1365221CM

PROSECO (A UK Multicentre Prospective Observational Study Evaluating COVID-19 Vaccine Immune Responses in Lymphoid Cancer)

University of Southampton, Faculty of Medicine, Cancer Sciences Unit, Experimental Cancer Medicine Centre

We are looking to appoint a highly motivated, full-time Laboratory Technician to support PROSECO, a clinical trial funded by the Vaccine Blood Cancer Research Consortium.  PROSECO is a UK multicentre observational study aimed at evaluating the robustness and persistence of immune responses in patients with lymphoid malignancies after COVID-19 vaccination.  Your role will be to support the Southampton Experimental Cancer Medicine Centre in undertaking the laboratory work associated with this study (peripheral blood mononuclear cell isolation, T, B, NK cell analysis using multicolour flow cytometry and T-cell ELISPOT), and the analysis of this data.  It is highly likely that the successful applicant will have an opportunity to co-author a publication from this study.

You will have relevant laboratory experience, display an ability to work flexibly and out-of-hours when necessary and to meet tight deadlines associated with this trial. 

The post holder will be primarily based in the WISH laboratory at the University Hospital Southampton. You will be required to comply with meticulous record-keeping and database management for all processes undertaken, as well as fully comply with requirements of GCP for laboratories. Training will be provided where necessary. There may be also the opportunity to work with other team members to carry out immunomonitoring assays in other clinical trial samples (e.g. flow cytometry, ELISA and immunohistochemistry assays).

You will require a good understanding of the current health and safety regulations and must undergo occupational health clearance for the job role. 

The appointment is a full time, 12 months fixed-term in the first instance, with a potential for a further 6 months' extension depending on performance and the progress of the trial.

For an informal discussion or to arrange a visit please contact Dr Sean Lim (s.h.lim@soton.ac.uk) or Dr Debora Joseph-Pietras (d.joseph-pietras@soton.ac.uk).

At the University of Southampton we promote equality and value diversity.

Application Procedure 

You should submit your completed online application form at https://jobs.soton.ac.uk. The application deadline will be midnight on the closing date stated above. If you need any assistance, please call Annabelle Trimm (Recruitment Team) on +44 (0) 23 8059 4043 or email recruitment@soton.ac.uk  Please quote reference 1365221CM on all correspondence.