Job Description

The successful candidate will work with Dr Gloryn Chia (NRF Fellow, Class of 2020) on establishing platforms for selecting immunogenic antigens under a project on vaccines.

We are seeking a highly motivated Research Fellow with keen interest and expertise in immunology, oncology and/or bioinformatics. Our team aims to leverage on stem cell biology (Sagi, Chia et. al., Nature 2016; Chia et. al., Nature Cell Biology 2019; Chia et. al., Nature Cell Biology 2017) and cell engineering to develop alternative immunotherapeutic strategies to target refractory cancer types. The candidate will work closely with clinicians to establish empirical platforms for identifying and validating cancer vaccine candidates, and to translate research findings into clinical practice. Also, the candidate will be involved in the assessment and development of vaccines against novel antigens for the treatment of cancer and other human diseases. The successful candidate is expected to independently design and execute experiments, troubleshoot issues, interpret results and give project updates. Highly motivated individuals with a passion for advancing personalized medicine are encouraged to apply. Our research is generously funded by the NRF Fellowship. We are located in iHealthTech, NUS, an interdisciplinary research centre that aims to bridge the gap between R&D in health technologies and eventual utility in the industry and bedside. A highly competitive remuneration package that commensurates with the qualifications and relevant experience of the successful candidate will be provided. For more information, please visit http://pharmacy.nus.edu.sg/gloryn-chia-laboratory/.

References

• Chia G, Agudo J, Treff N, Sauer MV, Billing D, Brown BD, Baer R, Egli D (2017). Genomic instability during reprogramming by nuclear transfer is DNA replication dependent. Nat Cell Biol; 19(4):282-291.
• Chia G*, Hu Z*, Tan DEK*, Tan H, Leong HF, Chen BJ, Lau MS, Tan KYS, Bi X, Yang D, Ho YS, Wu B, Bao S, Wong ESM, Tee WW (2020). Maternal factor NELFA drives a 2C-like state in mouse embryonic stem cells. Nat Cell Biol. doi:10.1038/s41556-019-0453-8. *co-first
• Sagi I, Chia G, Golan-Lev T, Peretz M, Sui L, Sauer M.V., Egli D, Benvenisty N (2016). Derivation and differentiation of haploid human embryonic stem cells. Nature; 7;532(7597):107-11.

Qualifications

Qualifications / Discipline:

Ph.D. in Biomedical Sciences or other relevant disciplines.

Skills:

Cell culture, analysis of clinical samples, molecular biology, etc.

Experience:

• Background and training in adaptive immunity.
• Strong publication track record, indicated by first author publications in high-quality journals.
• Knowledge and experience working with NGS datasets, bioinformatics (e.g. R), pipeline and assay development will be preferred.

More Information

Location: Kent Ridge Campus
Organization: Science
Department: Pharmacy
Employee Referral Eligible: No