PhD Scholarship in the Centre for Muscle Research
- Employer
- UNIVERSITY OF MELBOURNE
- Location
- Melbourne, Australia
- Closing date
- 7 Feb 2021
View more
- Academic Discipline
- Biological Sciences, Clinical, Pre-clinical & Health, Life sciences, Medicine & Dentistry
- Job Type
- Academic Posts, Studentships / Grants & Scholarships
- Contract Type
- Fixed Term
- Hours
- Full Time
Job Details
Work type: Fixed Term 3 years
Stipend: $31,200 p.a. (indexed, 2020 rate) for 3 years
This project will be conducted in the Centre for Muscle Research, Department of Anatomy & Physiology at the University of Melbourne, but will be co-supervised by our colleagues at the Karolinska Institute, Sweden and will encompass two months research at the Karolinska Institute. Based at the Parkville precinct our team bring combined expertise in the study of muscle in its many forms. We use innovative molecular and functional methods to study and understand muscle in both cell, animal and human based models. We have access to state-of-the-art facilities, mass spectrometry, metabolomics, gene expression technologies, histology, mouse phenotyping, muscle function platforms.
The project - “Mechanisms of amino acid signalling in skeletal muscle in critical illness"
Critical illness is associated with a very rapid decline in skeletal muscle mass and weakness. Impaired anabolic signalling has been proposed as a key contributor, yet despite its biological significance, the metabolic pathways responsible for nutrient sensing and regulation of protein synthesis remain unresolved. This research is an exciting collaboration between researchers at the Centre for Muscle Research, Intensivists (Melbourne Health) and specialists in metabolomics and autophagic flux measurements (Karolinska Institute, Sweden). The project is designed to increase our basic understanding of the skeletal muscle amino acid metabolism in critical illness and the amino acid sensing capacity of mTORC1. The fundamental discoveries will underpin development of muscle-specific modulators of muscle homeostasis with broad relevance to patients in intensive care. The outcomes of this Ph.D. project will provide an advance in knowledge and understanding of muscle and will provide advancements in novel therapies at a translational level.
Position Description
Applications close: 7 Feb 2021 11:55 PM AUS Eastern Daylight Time
Company
The University of Melbourne enjoys an outstanding reputation with world rankings consistently placing us as Australia’s leading comprehensive research-intensive university, and one of the world’s top 50*.
Melbourne attracts the best and brightest students and researchers and, with a history of over 160 years, we occupy a special place at the heart of our city’s cultural scene.
Melbourne is a leading research university, widely renowned for its teaching and the social and economic contributions it makes through knowledge transfer. The University’s performance in international rankings puts it at the forefront of higher education in the Asia-Pacific and beyond.
Internationally, the University is consistently ranked among the leading universities in the world, with its international peers placing it in the top 20 worldwide, and employers placing it in the top 10. In the recent Times Higher Education rankings of the world’s top 200 universities, Melbourne ranked top in Australia and 33 in the world.
Melbourne’s international research pre-eminence was also acknowledged with a top 100 ranking in the Shanghai Jiao Tong rankings. Ranked No. 44 in 2015, the University has climbed steadily in the rankings since first appearing at No. 92 in 2003.
The Melbourne Model introduces undergraduate programs characterised by both breadth and depth, followed by a graduate professional degree, a research higher degree or entry directly into employment.
In 2008 Melbourne commenced offering six New Generation undergraduate degrees in Arts, Biomedicine, Commerce, Environments, Music and Science. The Melbourne Model also introduces a new graduate school experience to Australia, providing the best and brightest with a more focused, intense and professionally relevant degree in areas such as Law, Architecture, Teaching and Nursing. With the Melbourne curriculum now aligning the University with the world’s top universities in Europe, North America and Asia, we enable our students to develop the skills and attributes required by employers all over the world.
More than 50,000 students from over 120 countries take courses in the University’s 12 faculties and graduate schools.
For more information please visit: http://www.unimelb.edu.au
*Times Higher Education World University Rankings 2015 – 2016 and Academic Ranking of World Universities 2015
- Mini-site
- UNIVERSITY OF MELBOURNE
- Telephone
- +61 (3) 8344 4000
- Location
-
Parkville
Melbourne
Victoria
VIC 3010
Australia
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