Research Fellow, Patrick G Johnston Centre for Cancer Research

Belfast, Northern Ireland
£33,797 to £40,322 per annum
Sep 14, 2020
End of advertisement period
Oct 14, 2020
Academic Discipline
Life sciences, Biological Sciences
Contract Type
Fixed Term
Full Time

Application closing date: 14/10/2020
Salary: £33,797 to £40,322 per annum
Job category/type: Research

Job description

This role will be based in the Patrick G Johnston Centre for Cancer Research and support a Cancer Research UK programme which aims to explore the relationship between DNA damage and immune response activation, in order to identify new strategies to stratify and treat breast cancer patients.

You will be involved in the characterisation of the molecular mechanisms responsible for DDRD-immune activation, following loss of specific genes or chemotherapeutic treatment and the identification of drugs that can activate the DDRD immune response for rational combination therapies with immune checkpoint blockade.

The successful candidate must have:

  • Have or be about to obtain a PhD in cancer biology, molecular biology or a related discipline.
  • At least 3-years relevant experience working in the field of cancer biology and/or immunology
  • Experience working with in vitro and in vivo models of cancer.
  • Experience with a range of molecular techniques, such as PCR, qPCR, IHC/ IF, WB, RNA-seq, NGS, CRISPR, IP (experience with at least 4 of these techniques is required).

Established in 2007, The Patrick G Johnston Centre for Cancer Research is a 5,000m2 purpose-built interdisciplinary centre, comprised of scientific teams from Biomedical Science, Clinical Medicine, Chemistry, Mathematics, Engineering and Radiobiology. The centre works collaboratively with partners around the world in order to translate research into innovative cancer treatments that enhance and extend life.

The Patrick G Johnston Centre for Cancer Research is the beating heart of a comprehensive cancer research programme in Belfast, focused on accelerating the delivery of scientific discovery to clinical application. The Patrick G Johnston Centre for Cancer Research is the research hub of the Belfast ECMC and the Belfast Experimental Cancer Medicine Centre (ECMC), operating in partnership with the Belfast Health and Social Care Trust. Our integrated clinical and scientific programmes address clinically unmet needs. Our principal objective is to promote evidence-based, innovative clinical trials in order to underpin improved patient outcomes in high incidence solid tumours of Gastro-Intestinal, Prostatic, Breast and Ovarian origin, and in specific Blood Cancers. Our unifying research theme is to develop translational outputs, in the form of biomarkers and/or novel therapeutic strategies that enable our Centre to be at the forefront of personalised cancer medicine in these prevalent diseases.

Queen’s University Belfast is a driver of innovation based on our talented, multinational workforce. Throughout the University, our academics are collaborating across disciplines to develop new discoveries and insights, working with outside agencies and institutions on projects of international significance. We are connected and networked with strategic partnerships across the world, helping us to expand our impact on wider society locally, nationally and globally. The University is committed to attracting, retaining and developing the best global talent within an environment that enables them to realise their full potential.

We are a leader in gender equality and diversity, and are one of the UK’s most successful universities in the Athena SWAN initiative which promotes gender equality and career progression. The School of Medicine, Dentistry and Biomedical Sciences works to actively drive and implement gender equality and are fully committed to the aims of the Athena SWAN Charter.  We currently hold a prestigious Athena SWAN Silver award which was successfully renewed in September 2016. We are ranked 1st in the UK for knowledge transfer partnerships, (Innovate UK) 9th in the UK for University facilities (Times Higher Education Student Experience Survey 2018) and 14th in the UK for research quality (Times and Sunday Times Good University Guide 2019).

Based in Belfast, a modern capital city, our beautiful campus is surrounded by abundant acres of parkland and is renowned as one of the safest and affordable cities in the UK. The choice of local Schools from pre-nursery upwards are some of the best available, and lovers of the outdoors can enjoy any number of activities from rowing and kayaking to top class golf among many others. We are immensely proud of what our city and our University will offer you.

For full job details and criteria please see the Candidate Information link on our website by clicking ‘apply’. You must clearly demonstrate how you meet the criteria when you submit your application. For further information please contact Resourcing Team, Queen's University Belfast, BT7 1NN. Telephone (028) 9097 3044 or email resourcing@qub.ac.uk.

The University is committed to equality of opportunity and to selection on merit. We welcome applications from all sections of society and particularly from people with a disability. 

Fixed term contract posts are available for the stated period in the first instance but, in particular circumstances, may be renewed or made permanent, subject to availability of funding.

Candidate Information
About the School
Furhter Information About the Centre
About the Group Leader Dr Kienan Savage
Further Information for International Applicants
Note to EEA Applicants on Brexit