This post is to work on a BBSRC-funded grant to investigate the role of an important chromatin modifying protein in controlling muscle stem cells during regeneration in zebrafish. The post holder will investigate the importance of the Polycomb Repressor Complex protein EZH2 in regulation of chromatin packaging, gene expression and cytoskeleton dynamics in muscle stem cells.
Using live cell imaging, immunolabelling and gene manipulation the post holder will investigate how manipulation of Ezh2 function and candidate target genes regulates muscle stem cell responses during regeneration.
A crucial requirement of the post holder is to therefore be comfortable working both independently and in a team. Applicants must have experience in molecular cloning, have excellent live cell imaging skills (ideally of zebrafish) and have an interest in utilizing cutting edge genomics techniques to explore the epigenetic regulation of gene expression. Experience in computational approaches to image analysis is desirable.
This post will be offered on a fixed-term contract for 15 months.
This is a full-time post – 100 % full time equivalent
The selection process will include a panel interview, an assessment, a presentation.
For an informal discussion to find out more about the role please contact Robert Knight on 020 7188 1798 or at firstname.lastname@example.org
To apply, please register with the King’s College London application portal and complete your application online.